Literature summary extracted from

Marverti, G.; Giuseppina Monti, M.; Pegg, A.E.; McCloskey, D.E.; Bettuzzi, S.; Ligabue, A.; Caporali, A.; DArca, D.; Moruzzi, M.S.
Spermidine/spermine N1-acetyltransferase transient overexpression restores sensitivity of resistant human ovarian cancer cells to N1,N12-bis(ethyl)spermine and to cisplatin (2005), Carcinogenesis, 26, 1677-1686.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.3.1.57	transfection of the SSAT repressed C13 cells with two expression vectors driving human SSAT overexpression by diverse promoters. SSAT overexpression inhibits cell growth and enhances growth sensitivity to N1,N12-bis(ethyl)spermine in C13 cells	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.57	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.3.1.57	ovary cancer cell	C13	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.57	acetyl-CoA + spermidine	-	Homo sapiens	CoA + N1-acetylspermidine	-	?

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Release 2023.1 (January 2023)