Literature summary extracted from

Copik, A.J.; Waterson, S.; Swierczek, S.I.; Bennett, B.; Holz, R.C.
Both nucleophile and substrate bind to the catalytic Fe(II)-center in the type-II methionyl aminopeptidase from Pyrococcus furiosus (2005), Inorg. Chem., 44, 1160-1162.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
3.4.11.18	electronic absorption spectrum in the absence and presence of both nitric oxide and the substrate-analog butaneboronic acid. Both bind to the catalytic Fe(II)-center of enzyme forming a complex that mimics an intermediate step between the Michaelis complex and the tetrahedral transition-state	Pyrococcus furiosus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.11.18	butaneboronic acid	substrate analog	Pyrococcus furiosus

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.4.11.18	Fe2+	-	Pyrococcus furiosus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.11.18	Pyrococcus furiosus	-	type II enzyme	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)