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Literature summary extracted from

  • Lisa, T.A.; Garrido, M.N.; Domenech, C.E.
    Pseudomonas aeruginosa acid phosphatase and cholinesterase induced by choline and its metabolic derivatives may contain a similar anionic peripheral site (1984), Mol. Cell. Biochem., 63, 113-118.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.2 additional information the enzyme is induced by choline and its metabolic derivatives, most effectively by betaine and dimethylglycine, low induction by sarcosine, poor induction by glycine and ethanolamine, choline, phosphorylcholine, and betaine are inhibitory in vitro Pseudomonas aeruginosa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.2 atropine substrate 4-nitrophenyl phosphate slightly increases the inhibitory effect Pseudomonas aeruginosa
3.1.3.2 betaine
-
 Pseudomonas aeruginosa
3.1.3.2 choline
-
 Pseudomonas aeruginosa
3.1.3.2 decamethonium substrate 4-nitrophenyl phosphate slightly increases the inhibitory effect Pseudomonas aeruginosa
3.1.3.2 gallamine substrate 4-nitrophenyl phosphate slightly decreases the inhibitory effect Pseudomonas aeruginosa
3.1.3.2 additional information the enzyme is induced by choline and its metabolic derivatives, most effectively by betaine and dimethylglycine, low induction by sarcosine, poor induction by glycine and ethanolamine, but choline, phosphorylcholine, and betaine are inhibitory in vitro Pseudomonas aeruginosa
3.1.3.2 neostigmine substrate 4-nitrophenyl phosphate slightly increases the inhibitory effect Pseudomonas aeruginosa
3.1.3.2 phosphoryl choline
-
 Pseudomonas aeruginosa
3.1.3.2 procaine substrate 4-nitrophenyl phosphate slightly decreases the inhibitory effect Pseudomonas aeruginosa
3.1.3.2 tubocurarine substrate 4-nitrophenyl phosphate slightly decreases the inhibitory effect Pseudomonas aeruginosa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.2 Mg2+
-
 Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.2 Pseudomonas aeruginosa
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.2 additional information
-
 activity in cell culture grown in presence of different inducing compounds Pseudomonas aeruginosa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.2 4-nitrophenyl phosphate + H2O
-
 Pseudomonas aeruginosa 4-nitrophenol + phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.3.2 37
-
 assay at Pseudomonas aeruginosa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.2 5
-
 assay at Pseudomonas aeruginosa