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Literature summary extracted from

  • Nichols, C.E.; Ren, J.; Leslie, K.; Dhaliwal, B.; Lockyer, M.; Charles, I.; Hawkins, A.R.; Stammers, D.K.
    Comparison of ligand-induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases (2004), J. Mol. Biol., 343, 533-546.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.2.3.4 sitting-drop vapour-diffusion crystallisation at 4°C utilising microbridges, crystals of unliganded enzyme as well as in complexes with NAD+, the substrate analogue [1R-(1alpha,3beta,4alpha,5beta)]-5-phosphonomethyl-1,3,4-trihydroxycyclohexane-1-carboxylic acid and together with both, NAD+ and [1R-(1alpha,3beta,4alpha,5beta)]-5-phosphonomethyl-1,3,4-trihydroxycyclohexane-1-carboxylic acid Aspergillus nidulans
4.2.3.4 sitting-drop vapour-diffusion crystallisation at 4°C utilising microbridges, crystals of unliganded enzyme as well as in complexes with NAD, the substrate analogue [1R-(1alpha,3beta,4alpha,5beta)]-5-phosphonomethyl-1,3,4-trihydroxycyclohexane-1-carboxylic acid and together with both, NAD and [1R-(1alpha,3beta,4alpha,5beta)]-5-phosphonomethyl-1,3,4-trihydroxycyclohexane-1-carboxylic acid Staphylococcus aureus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.2.3.4 Co2+
-
 Aspergillus nidulans
4.2.3.4 Co2+
-
 Staphylococcus aureus

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.4 Aspergillus nidulans P07547
-
-
4.2.3.4 Staphylococcus aureus Q6GGU4
-
-

Synonyms

EC Number Synonyms Comment Organism
4.2.3.4 dehydroquinate synthase
-
 Aspergillus nidulans
4.2.3.4 dehydroquinate synthase
-
 Staphylococcus aureus

Cofactor

EC Number Cofactor Comment Organism Structure
4.2.3.4 NAD+
-
 Aspergillus nidulans
4.2.3.4 NAD+
-
 Staphylococcus aureus