EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(3,5-difluoro)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(3-carboxylic)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(3-fluoro)phenylcyclo-hex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(3-hydroxy)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(3-nitro)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(3-trifluoromethyl)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(4-fluoro)phenylcyclo-hex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(4-trifluoromethyl)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(furan-3-yl)phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(pyridine-3-yl)cyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-(thiophen-3-yl)phenyl-cyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis | |
4.2.1.10 | (1R,3R,4R)-1,3,4-trihydroxy-5-phenylcyclohex-5-en-1-carboxylic acid | - |
Mycobacterium tuberculosis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.2.1.10 | Mycobacterium tuberculosis | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.2.1.10 | 3-dehydroquinate | - |
Mycobacterium tuberculosis | 3-dehydroshikimate + H2O | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.2.1.10 | 0.054 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(3-nitro)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 0.59 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(thiophen-3-yl)phenyl-cyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 0.83 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(furan-3-yl)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 1.5 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 1.5 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(3-fluoro)phenylcyclo-hex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 1.8 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(4-fluoro)phenylcyclo-hex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 2.125 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(3-trifluoromethyl)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 2.44 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(3,5-difluoro)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 17 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(4-trifluoromethyl)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 45 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(pyridine-3-yl)cyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 95 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(3-hydroxy)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis | |
4.2.1.10 | 150 | - |
(1R,3R,4R)-1,3,4-trihydroxy-5-(3-carboxylic)phenylcyclohex-5-en-1-carboxylic acid | pH 8.2, 25°C | Mycobacterium tuberculosis |