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Literature summary extracted from

  • Ingraham, J.L.; Neuhard, J.
    Cold-sensitive mutants of Salmonella typhimurium defective in uridine monophosphate kinase (pyrH) (1972), J. Biol. Chem., 247, 6259-6265.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.22 ATP + UMP Salmonella enterica subsp. enterica serovar Typhimurium
-
 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP Salmonella enterica subsp. enterica serovar Typhimurium JL1220
-
 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP Salmonella enterica subsp. enterica serovar Typhimurium JL1269
-
 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP Salmonella enterica subsp. enterica serovar Typhimurium JL1019
-
 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP Salmonella enterica subsp. enterica serovar Typhimurium JL1219
-
 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP Salmonella enterica subsp. enterica serovar Typhimurium KP1217
-
 ADP + UDP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium P65933 uracil, genotype: pyrC1502
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium P65933 genotype: pyrH1608, udk+
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium P65933 genotype: pyrH1609, udk-10
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium P65933 genotype: pyrH1609, udk+
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium P65933 genotype: pyrH+, udk+
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium JL1019 P65933 uracil, genotype: pyrC1502
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium JL1219 P65933 genotype: pyrH1608, udk+
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium JL1220 P65933 genotype: pyrH1609, udk-10
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium JL1269 P65933 genotype: pyrH1609, udk+
-
2.7.4.22 Salmonella enterica subsp. enterica serovar Typhimurium KP1217 P65933 genotype: pyrH+, udk+
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.4.22 0.003
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.006
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.011
-
 0-45% ammonium sulfate precipitate Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.014
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.018
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.019
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.031
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.033
-
 45-55% ammonium sulfate precipitate Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 0.053
-
 55-80% ammonium sulfate precipitate Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.22 ATP + UMP
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + UDP
-
 ?
2.7.4.22 ATP + UMP 37°C, pH 7.8, 7.5 mM MgCl2 Salmonella enterica subsp. enterica serovar Typhimurium ADP + UDP
-
 ?
2.7.4.22 ATP + UMP
-
 Salmonella enterica subsp. enterica serovar Typhimurium JL1220 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP 37°C, pH 7.8, 7.5 mM MgCl2 Salmonella enterica subsp. enterica serovar Typhimurium JL1220 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP
-
 Salmonella enterica subsp. enterica serovar Typhimurium JL1269 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP 37°C, pH 7.8, 7.5 mM MgCl2 Salmonella enterica subsp. enterica serovar Typhimurium JL1269 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP
-
 Salmonella enterica subsp. enterica serovar Typhimurium JL1019 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP 37°C, pH 7.8, 7.5 mM MgCl2 Salmonella enterica subsp. enterica serovar Typhimurium JL1019 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP
-
 Salmonella enterica subsp. enterica serovar Typhimurium JL1219 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP 37°C, pH 7.8, 7.5 mM MgCl2 Salmonella enterica subsp. enterica serovar Typhimurium JL1219 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP
-
 Salmonella enterica subsp. enterica serovar Typhimurium KP1217 ADP + UDP
-
 ?
2.7.4.22 ATP + UMP 37°C, pH 7.8, 7.5 mM MgCl2 Salmonella enterica subsp. enterica serovar Typhimurium KP1217 ADP + UDP
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.4.22 UMP kinase
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.7.4.22 uridine monophosphate kinase
-
 Salmonella enterica subsp. enterica serovar Typhimurium