Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kehlen, A.; Englert, N.; Seifert, A.; Klonisch, T.; Dralle, H.; Langner, J.; Hoang-Vu, C.
    Expression, regulation and function of autotaxin in thyroid carcinomas (2004), Int. J. Cancer, 109, 833-838.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.39 bFGF induces a 1.9fold higher ATX mRNA expression Homo sapiens
3.1.4.39 EGF induces a 2.3fold higher ATX mRNA expression Homo sapiens
3.1.4.39 IL-6 induces a marked increase in ATX mRNA expression Homo sapiens

Application

EC Number Application Comment Organism
3.1.4.39 medicine tumor cell motility-stimulating factor Homo sapiens
3.1.4.39 molecular biology is involved in the regulation of IL-8 and CD54 gene Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.39 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.39 thyroid cancer cell line
-
 Homo sapiens
-

Storage Stability

EC Number Storage Stability Organism
3.1.4.39 -80°C Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.39 lysophosphatidylcholine + H2O
-
 Homo sapiens lysophosphatidic acid + choline
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.39 ATX/NPP2
-
 Homo sapiens
3.1.4.39 autotaxin
-
 Homo sapiens
3.1.4.39 lysophospholipase D
-
 Homo sapiens
3.1.4.39 lysoPLD
-
 Homo sapiens