EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.2 | additional information | - |
additional information | kinetic mechanism | Streptomyces coelicolor | |
2.7.1.2 | additional information | - |
additional information | kinetic mechanism | Streptomyces peucetius subsp. caesius |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.1.2 | cytosol | over 96% of the enzyme content in the cell | Streptomyces coelicolor | 5829 | - |
2.7.1.2 | cytosol | over 96% of the enzyme content in the cell | Streptomyces peucetius subsp. caesius | 5829 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.2 | Mg2+ | as MgATP2- | Streptomyces coelicolor | |
2.7.1.2 | Mg2+ | as MgATP2- | Streptomyces peucetius subsp. caesius |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.2 | ATP + D-glucose | Streptomyces coelicolor | - |
ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.2 | ATP + D-glucose | Streptomyces peucetius subsp. caesius | - |
ADP + D-glucose 6-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.2 | Streptomyces coelicolor | P0A4E1 | no isozymes | - |
2.7.1.2 | Streptomyces peucetius subsp. caesius | - |
no isozymes | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.2 | - |
Streptomyces coelicolor |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.7.1.2 | ATP + D-glucose = ADP + D-glucose 6-phosphate | rapid equilibrium-ordered bi bi sequential mechanism, formation of a ternary complex of enzyme-D-glucose-MgATP2- | Streptomyces coelicolor | |
2.7.1.2 | ATP + D-glucose = ADP + D-glucose 6-phosphate | rapid equilibrium-ordered bi bi sequential mechanism, formation of a ternary complex of enzyme-D-glucose-MgATP2- | Streptomyces peucetius subsp. caesius |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.1.2 | 1.09 | - |
purified enzyme, Vmax | Streptomyces peucetius subsp. caesius |
2.7.1.2 | 1.67 | - |
purified enzyme, Vmax | Streptomyces coelicolor |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.2 | ATP + D-glucose | - |
Streptomyces coelicolor | ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.2 | ATP + D-glucose | - |
Streptomyces peucetius subsp. caesius | ADP + D-glucose 6-phosphate | - |
? | |
2.7.1.2 | additional information | comparison of the biochemical properties to those of the enzyme from Streptomyces coelicolor | Streptomyces peucetius subsp. caesius | ? | - |
? | |
2.7.1.2 | additional information | comparison of the biochemical properties to those of the enzyme from Streptomyces peucetius var. caesius | Streptomyces coelicolor | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.2 | dimer | - |
Streptomyces peucetius subsp. caesius |
2.7.1.2 | tetramer | stable form | Streptomyces coelicolor |
2.7.1.2 | tetramer | unstable form, rapid dissociation to dimers | Streptomyces peucetius subsp. caesius |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.2 | glk | - |
Streptomyces coelicolor |
2.7.1.2 | glk | - |
Streptomyces peucetius subsp. caesius |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.1.2 | 33 | - |
- |
Streptomyces coelicolor |
2.7.1.2 | 42 | - |
- |
Streptomyces peucetius subsp. caesius |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.2 | ATP | as MgATP2- | Streptomyces coelicolor | |
2.7.1.2 | ATP | as MgATP2- | Streptomyces peucetius subsp. caesius |