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Literature summary extracted from

  • Islam, M.N.; Sueda, S.; Kondo, H.
    Construction of new forms of pyruvate carboxylase to assess the allosteric regulation by acetyl-CoA (2005), PROTEIN ENG. DES. SEL., 18, 71-78.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.4.1.1 acetyl-CoA
-
 Geobacillus thermodenitrificans

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.4.1.1 expression of the subunits biotin carboxylase BC and carboxyl transferase CT (PC-(BC+CT)) and biotin carboxyl carrier protein BCCP (PC-(BCCP)) in Escherichia coli JM109 Geobacillus thermodenitrificans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.4.1.1 0.039
-
 pyruvate
-
 Geobacillus thermodenitrificans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.4.1.1 ATP + pyruvate + HCO3- Geobacillus thermodenitrificans
-
 ADP + oxaloacetate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.1 Geobacillus thermodenitrificans
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.4.1.1
-
 Geobacillus thermodenitrificans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.1 ATP + pyruvate + HCO3-
-
 Geobacillus thermodenitrificans ADP + oxaloacetate + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.4.1.1 PC
-
 Geobacillus thermodenitrificans