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Literature summary extracted from
- Proton translocation by transhydrogenase (2003), FEBS Lett., 545, 18-24.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.1.1.1 | membrane | - |
Escherichia coli | 16020 | - |
| 7.1.1.1 | membrane | - |
Rhodospirillum rubrum | 16020 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.1 | NADH + NADP+ | Escherichia coli | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r |  |
| 7.1.1.1 | NADH + NADP+ | Rhodospirillum rubrum | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | NAD+ + NADPH | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.1 | Escherichia coli | - |
- |
- |
| 7.1.1.1 | Rhodospirillum rubrum | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.1 | NADH + NADP+ | - |
Escherichia coli | NAD+ + NADPH | - |
r | |
| 7.1.1.1 | NADH + NADP+ | - |
Rhodospirillum rubrum | NAD+ + NADPH | - |
r | |
| 7.1.1.1 | NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | Escherichia coli | NAD+ + NADPH | - |
r | |
| 7.1.1.1 | NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, provides NADPH for biosynthesis and reduction of glutathione | Rhodospirillum rubrum | NAD+ + NADPH | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.1.1.1 | dimer | monomers composed of three domains, dI, dII, and dIII | Escherichia coli |
| 7.1.1.1 | dimer | monomers composed of three domains, dI, dII, and dIII | Rhodospirillum rubrum |
| 7.1.1.1 | trimer | dI2dIII trimers formed in mixtures of recombinant dI and dIII domains | Escherichia coli |
| 7.1.1.1 | trimer | dI2dIII trimers formed in mixtures of recombinant dI and dIII domains | Rhodospirillum rubrum |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.1 | NAD(P)+ | - |
Escherichia coli | |
| 7.1.1.1 | NAD(P)+ | - |
Rhodospirillum rubrum | |
| 7.1.1.1 | NAD(P)H | - |
Escherichia coli | |
| 7.1.1.1 | NAD(P)H | - |
Rhodospirillum rubrum | |
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Release 2023.1 (January 2023)
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