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Literature summary extracted from

  • Patel, R.N.; Banerjee, A.; Ko, R.Y.; Howell, J.M.; Li, W.S.; Comezoglu, F.T.
    Enzymic preparation of (3R-cis)-3-acetyloxy-4-phenyl-2-azetidinone: a taxol side-chain synthon (1994), Biotechnol. Appl. Biochem., 20, 23-33.
No PubMed abstract available

Application

EC Number Application Comment Organism
3.1.1.3 synthesis production of (3R,4S)-cis-azetidinone acetate, which is an intermediate for the synthesis of paclitaxel Burkholderia cepacia

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.3 Burkholderia cepacia
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.3 cis-3-(acetyloxy)-4-phenyl-2-azetidinone + H2O
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Burkholderia cepacia (3R,4S)-cis-3-(acetyloxy)-4-phenyl-2-azetidinone + (3S,4R)-cis-3-hydroxy-4-phenyl-2-azetidinone + acetate
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?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.3 29
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Burkholderia cepacia

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.3 7
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-
Burkholderia cepacia