EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.33 | 1-(((2,4,6-trimethylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.017 mM | Glycine max | |
1.13.11.33 | 1-(((2,4-dimethoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.027 mM | Glycine max | |
1.13.11.33 | 1-(((2,5-dimethoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.015 mM | Glycine max | |
1.13.11.33 | 1-(((2-methyl)ethylsulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.042 mM | Glycine max | |
1.13.11.33 | 1-(((2-methyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.022 mM | Glycine max | |
1.13.11.33 | 1-(((2-thienyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.021 mM | Glycine max | |
1.13.11.33 | 1-(((3,4-dimethoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.019 mM | Glycine max | |
1.13.11.33 | 1-(((3-thienyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.023 mM | Glycine max | |
1.13.11.33 | 1-(((4-(2-methylethyl)phenl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.016 mM | Glycine max | |
1.13.11.33 | 1-(((4-chlorophenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.022 mM | Glycine max | |
1.13.11.33 | 1-(((4-methoxyphenyl)sulfonyl)oxy)-2,3-bis(4-methylphenyl)-7-indolizinecarbonitrile | IC50: 0.025 mM | Glycine max | |
1.13.11.33 | 1-(((4-methoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.025 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-chlorophenyl)-7-indolizinecarbonitrile | IC50: 0.2 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-fluorophenyl)-7-indolizinecarbonitrile | IC50: 0.22 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-methoxyphenyl)-7-indolizinecarbonitrile | IC50: 0.024 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-methylphenyl)-7-indolizinecarbonitrile | IC50: 0.2 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-dibutyl-7-indolizinecarbonitrile | IC50: 0.03 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-diethyl-7-indolizinecarbonitrile | IC50: 0.029 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarboxaldehyde | IC50: 0.02 mM | Glycine max | |
1.13.11.33 | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinylethanone | IC50: 0.023 mM | Glycine max | |
1.13.11.33 | 1-(((4-methysulfonyllphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.024 mM | Glycine max | |
1.13.11.33 | 1-(((4-trifluoromethylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.023 mM | Glycine max | |
1.13.11.33 | 1-((4-methylphenyl)sulfonyl)2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.029 mM | Glycine max | |
1.13.11.33 | 1-((butylsulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.028 mM | Glycine max | |
1.13.11.33 | 1-((methylsulfonyl)oxy)-2,3-diphenyl-7-indolizine-carbonitrile | IC50: 0.022 mM | Glycine max | |
1.13.11.33 | 1-((N,N-dimethylaminosulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.025 mM | Glycine max | |
1.13.11.33 | 1-((phenylsulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | IC50: 0.024 mM | Glycine max | |
1.13.11.33 | 2,3-bis(4-chlorophenyl)-7-indolizinecarbonitrile | IC50: 0.033 mM | Glycine max | |
1.13.11.33 | 2,3-bis(4-fluorophenyl)-7-indolizinecarbonitrile | IC50: 0.03 mM | Glycine max | |
1.13.11.33 | 2,3-bis(4-methylphenyl)-7-indolizinecarbonitrile | IC50: 0.027 mM | Glycine max | |
1.13.11.33 | 2,3-diphenyl-1-indolizinol tosylate | IC50: 0.025 mM | Glycine max | |
1.13.11.33 | 6,7-diphenylpyrrolo[1,2-a]pyrimidin-8-ol tosylate | IC50: 0.015 mM | Glycine max | |
1.13.11.33 | 6,7-diphenylpyrrolo[1,2-c]pyrimidin-5-ol tosylate | IC50: 0.022 mM | Glycine max | |
1.13.11.33 | 7-(1,1-dimethylethyl)-2,3-diphenyl-1-indolizinol tosylate | IC50: 0.022 mM | Glycine max |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.33 | Glycine max | - |
- |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.13.11.33 | 15-LO | - |
Glycine max |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.13.11.33 | 0.015 | - |
IC50: 0.015 mM | Glycine max | 1-(((2,5-dimethoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.015 | - |
IC50: 0.015 mM | Glycine max | 6,7-diphenylpyrrolo[1,2-a]pyrimidin-8-ol tosylate | |
1.13.11.33 | 0.016 | - |
IC50: 0.016 mM | Glycine max | 1-(((4-(2-methylethyl)phenl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.017 | - |
IC50: 0.017 mM | Glycine max | 1-(((2,4,6-trimethylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.019 | - |
IC50: 0.019 mM | Glycine max | 1-(((3,4-dimethoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.02 | - |
IC50: 0.02 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarboxaldehyde | |
1.13.11.33 | 0.021 | - |
IC50: 0.021 mM | Glycine max | 1-(((2-thienyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.022 | - |
IC50: 0.022 mM | Glycine max | 7-(1,1-dimethylethyl)-2,3-diphenyl-1-indolizinol tosylate | |
1.13.11.33 | 0.022 | - |
IC50: 0.022 mM | Glycine max | 1-((methylsulfonyl)oxy)-2,3-diphenyl-7-indolizine-carbonitrile | |
1.13.11.33 | 0.022 | - |
IC50: 0.022 mM | Glycine max | 1-(((2-methyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.022 | - |
IC50: 0.022 mM | Glycine max | 1-(((4-chlorophenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.022 | - |
IC50: 0.022 mM | Glycine max | 6,7-diphenylpyrrolo[1,2-c]pyrimidin-5-ol tosylate | |
1.13.11.33 | 0.023 | - |
IC50: 0.023 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinylethanone | |
1.13.11.33 | 0.023 | - |
IC50: 0.023 mM | Glycine max | 1-(((3-thienyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.023 | - |
IC50: 0.023 mM | Glycine max | 1-(((4-trifluoromethylphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.024 | - |
IC50: 0.024 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-methoxyphenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.024 | - |
IC50: 0.024 mM | Glycine max | 1-((phenylsulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.024 | - |
IC50: 0.024 mM | Glycine max | 1-(((4-methysulfonyllphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.025 | - |
IC50: 0.025 mM | Glycine max | 2,3-diphenyl-1-indolizinol tosylate | |
1.13.11.33 | 0.025 | - |
IC50: 0.025 mM | Glycine max | 1-((N,N-dimethylaminosulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.025 | - |
IC50: 0.025 mM | Glycine max | 1-(((4-methoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.025 | - |
IC50: 0.025 mM | Glycine max | 1-(((4-methoxyphenyl)sulfonyl)oxy)-2,3-bis(4-methylphenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.027 | - |
IC50: 0.027 mM | Glycine max | 1-(((2,4-dimethoxyphenyl)sulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.027 | - |
IC50: 0.027 mM | Glycine max | 2,3-bis(4-methylphenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.028 | - |
IC50: 0.028 mM | Glycine max | 1-((butylsulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.029 | - |
IC50: 0.029 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-diethyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.029 | - |
IC50: 0.029 mM | Glycine max | 1-((4-methylphenyl)sulfonyl)2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.03 | - |
IC50: 0.03 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-dibutyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.03 | - |
IC50: 0.03 mM | Glycine max | 2,3-bis(4-fluorophenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.033 | - |
IC50: 0.033 mM | Glycine max | 2,3-bis(4-chlorophenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.042 | - |
IC50: 0.042 mM | Glycine max | 1-(((2-methyl)ethylsulfonyl)oxy)-2,3-diphenyl-7-indolizinecarbonitrile | |
1.13.11.33 | 0.2 | - |
IC50: 0.2 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-chlorophenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.2 | - |
IC50: 0.2 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-methylphenyl)-7-indolizinecarbonitrile | |
1.13.11.33 | 0.22 | - |
IC50: 0.22 mM | Glycine max | 1-(((4-methylphenyl)sulfonyl)oxy)-2,3-bis(4-fluorophenyl)-7-indolizinecarbonitrile |