Any feedback?
Literature summary extracted from
- MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51 (2005), Biochim. Biophys. Acta, 1707, 157-169.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.18.1.3 | expressed in Escherichia coli MV1304 as GST-fusion protein | Mycobacterium tuberculosis |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 1.18.1.3 | 43000 | - |
x * 69000, SDS-PAGE, GST-fusion protein, x * 43000, SDS-PAGE, native protein | Mycobacterium tuberculosis |
| 1.18.1.3 | 69000 | - |
x * 69000, SDS-PAGE, GST-fusion protein, x * 43000, SDS-PAGE, native protein | Mycobacterium tuberculosis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.18.1.3 | oxidized ferredoxin + NADH | Mycobacterium tuberculosis | required for activity of CYP101 | reduced ferredoxin + NAD+ | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.18.1.3 | Mycobacterium tuberculosis | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.18.1.3 | recombinant protein | Mycobacterium tuberculosis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.18.1.3 | oxidized ferredoxin + NADH | - |
Mycobacterium tuberculosis | reduced ferredoxin + NAD+ | - |
? | |
| 1.18.1.3 | oxidized ferredoxin + NADH | required for activity of CYP101 | Mycobacterium tuberculosis | reduced ferredoxin + NAD+ | - |
? | |
| 1.18.1.3 | oxidized ferredoxin + NADPH | - |
Mycobacterium tuberculosis | reduced ferredoxin + NADP+ | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 1.18.1.3 | ? | x * 69000, SDS-PAGE, GST-fusion protein, x * 43000, SDS-PAGE, native protein | Mycobacterium tuberculosis |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.18.1.3 | FdR | - |
Mycobacterium tuberculosis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.18.1.3 | FAD | associated to enzyme, 0.6-0.8 FAD per protein monomer | Mycobacterium tuberculosis | |
| 1.18.1.3 | NADH | preferred cofactor | Mycobacterium tuberculosis | |
| 1.18.1.3 | NADPH | much less effective cofactor than NADH | Mycobacterium tuberculosis | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
