EC Number | Crystallization (Comment) | Organism |
---|---|---|
1.8.98.2 | crystals of the wild-type and SeMet forms of ET-hSrx were obtained by the vapor diffusion method. 1.65 A crystal structure of human Srx | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH | Homo sapiens | repairs the inactivated forms of typical two-Cys peroxiredoxins implicated in hydrogen peroxide-mediated cell signaling | peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.98.2 | Homo sapiens | Q9BYN0 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.98.2 | - |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH | repairs the inactivated forms of typical two-Cys peroxiredoxins implicated in hydrogen peroxide-mediated cell signaling | Homo sapiens | peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? | |
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH | the ATP molecule is cleaved between the beta- and gamma-phosphate groups | Homo sapiens | peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.98.2 | peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase | - |
Homo sapiens |
1.8.98.2 | Srx | - |
Homo sapiens |
1.8.98.2 | sulphiredoxin | - |
Homo sapiens |