Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ucar, G.; Tas, C.; Tuemer, A.
    Monoamine oxidase inhibitory activities of the scorpion Mesobuthus gibbosus (Buthidae) venom peptides (2005), Toxicon, 45, 43-52.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 Clorgyline
-
 Rattus norvegicus
1.4.3.4 Mesobuthus gibbosus venom peptide with specific MAO-A inhibitory activity, reversible, non-competitive, may be responsible for the anxiogenic effects of the scorpion venom on animals and humans Rattus norvegicus
1.4.3.4 additional information no inhibition by Mesobuthus gibbosus venom peptide Homo sapiens
1.4.3.4 additional information no inhibition by Mesobuthus gibbosus venom peptide Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.4 0.02031
-
 p-tyramine
-
 Rattus norvegicus
1.4.3.4 0.061
-
 p-tyramine
-
 Rattus norvegicus
1.4.3.4 0.19
-
 p-tyramine
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrion
-
 Homo sapiens 5739
-
1.4.3.4 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Homo sapiens
-
-
-
1.4.3.4 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.4
-
 Homo sapiens
1.4.3.4
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 blood platelet
-
 Homo sapiens
-
1.4.3.4 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 p-tyramine + H2O + O2
-
 Homo sapiens (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 p-tyramine + H2O + O2
-
 Rattus norvegicus (4-hydroxyphenyl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
 Rattus norvegicus
1.4.3.4 MAO-B
-
 Homo sapiens
1.4.3.4 MAO-B
-
 Rattus norvegicus
1.4.3.4 monoamine oxidase A
-
 Rattus norvegicus
1.4.3.4 monoamine oxidase B
-
 Homo sapiens
1.4.3.4 monoamine oxidase B
-
 Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.4 additional information
-
 additional information
-
 Rattus norvegicus