EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.4.3.22 | 1,10-phenanthroline | 10 mM, 47% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | 2-mercaptoethanol | 10 mM, 26% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | 8-hydroxyquinoline | 10 mM, 24% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | alpha,alpha'-dipyridyl | 10 mM, 22% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | Diethyl dithiocarbamate | 10 mM, 76% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | dithiothreitol | 10 mM, 12% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | EDTA | 10 mM, 18% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | hydrazine | 10 mM, 95% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | Iproniazide | 10 mM, 43% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | isoniazide | 10 mM, 76% inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | methylhydrazine | 10 mM, complete inhibition | Arthrobacter crystallopoietes | |
1.4.3.22 | N,N-diethyldithiocarbamate | the inactive enzyme is restored with Cu2+ to 65% of its initial activity | Arthrobacter crystallopoietes | |
1.4.3.22 | phenylhydrazine | 10 mM, complete inhibition | Arthrobacter crystallopoietes |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.4.3.22 | 0.51 | - |
histamine | pH 7.0, 37°C | Arthrobacter crystallopoietes |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.4.3.22 | copper | one atom of copper per mol of enzyme protein | Arthrobacter crystallopoietes | |
1.4.3.22 | Cu2+ | a part of the apoenzyme is reconstituted in presence of Cu2+ | Arthrobacter crystallopoietes | |
1.4.3.22 | MgSO4 | 10 mM, activation to 114% of control | Arthrobacter crystallopoietes |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.4.3.22 | 81000 | - |
gel filtration, native PAGE | Arthrobacter crystallopoietes |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.3.22 | Arthrobacter crystallopoietes | - |
KAIT-B-007 | - |
1.4.3.22 | Arthrobacter crystallopoietes KAIT-B-007 | - |
KAIT-B-007 | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.4.3.22 | - |
Arthrobacter crystallopoietes |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.4.3.22 | 14.3 | - |
- |
Arthrobacter crystallopoietes |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.3.22 | 1-phenylethylamine + H2O + O2 | 44% of the activity with histamine | Arthrobacter crystallopoietes | 1-phenylethanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | 1-phenylethylamine + H2O + O2 | 44% of the activity with histamine | Arthrobacter crystallopoietes KAIT-B-007 | 1-phenylethanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | agmatine + H2O + O2 | 4% of the activity with histamine | Arthrobacter crystallopoietes | ? | - |
? | |
1.4.3.22 | agmatine + H2O + O2 | 4% of the activity with histamine | Arthrobacter crystallopoietes KAIT-B-007 | ? | - |
? | |
1.4.3.22 | butylamine + H2O + O2 | 22% of the activity with histamine | Arthrobacter crystallopoietes | butanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | dopamine + H2O + O2 | 51% of the activity with histamine | Arthrobacter crystallopoietes | 2-(3,4-dihydroxyphenyl)ethanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | hexylamine + H2O + O2 | 41% of the activity with histamine | Arthrobacter crystallopoietes | hexanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | histamine + H2O + O2 | - |
Arthrobacter crystallopoietes | (imidazol-4-yl)acetaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.22 | histamine + H2O + O2 | - |
Arthrobacter crystallopoietes KAIT-B-007 | (imidazol-4-yl)acetaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.22 | additional information | no activity with putrescine, cadaverine, spermine, and spermidine | Arthrobacter crystallopoietes | ? | - |
? | |
1.4.3.22 | additional information | no activity with putrescine, cadaverine, spermine, and spermidine | Arthrobacter crystallopoietes KAIT-B-007 | ? | - |
? | |
1.4.3.22 | pentylamine + H2O + O2 | 32% of the activity with histamine | Arthrobacter crystallopoietes | pentanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | propylamine + H2O + O2 | 7% of the activity with histamine | Arthrobacter crystallopoietes | propanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | tryptamine + H2O + O2 | 15% of the activity with histamine | Arthrobacter crystallopoietes | 1H-indol-3-ylacetaldehyde + NH3 + H2O2 | - |
? | |
1.4.3.22 | tyramine + H2O + O2 | 36% of the activity with histamine | Arthrobacter crystallopoietes | 4-hydroxyphenylethanal + NH3 + H2O2 | - |
? | |
1.4.3.22 | tyramine + H2O + O2 | 36% of the activity with histamine | Arthrobacter crystallopoietes KAIT-B-007 | 4-hydroxyphenylethanal + NH3 + H2O2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.4.3.22 | monomer | 1 * 81000, SDS-PAGE | Arthrobacter crystallopoietes |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.4.3.22 | histamine oxidase | - |
Arthrobacter crystallopoietes |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.4.3.22 | 65 | - |
10 min, stable | Arthrobacter crystallopoietes |
1.4.3.22 | 70 | - |
10 min, 93% inactivation | Arthrobacter crystallopoietes |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.4.3.22 | 9 | - |
- |
Arthrobacter crystallopoietes |
EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|---|
1.4.3.22 | 6 | 9 | 37°C, 30 min, stable | Arthrobacter crystallopoietes |