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Literature summary extracted from

  • Anfuso, C.D.; Sipione, S.; Lupo, G.; Ragusa, N.; Alberghina, M.
    Characterization of glycerophosphocholine phosphodiesterase activity and phosphatidylcholine biosynthesis in cultured retinal microcapillary pericytes. Effect of adenosine and endothelin-1 (2003), Lipids, 38, 45-52.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.4.2 Ca2+
-
 Bos taurus
3.1.4.2 Cu2+
-
 Bos taurus
3.1.4.2 Mg2+
-
 Bos taurus
3.1.4.2 Zn2+
-
 Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.2 EDTA at 1 mM, about 85% inhibition Bos taurus
3.1.4.2 N-ethylmaleimide at 3 mM, about 30% inhibition Bos taurus
3.1.4.2 p-chloromercuribenzoate at 0.1 mM, about 25% inhibition Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.2 0.31
-
 sn-glycero 3-phosphorylcholine pH 8.0, 37°C Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.4.2 microsome minority of enzymic activity Bos taurus
-
-
3.1.4.2 plasma membrane majority of enzymic activity Bos taurus 5886
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.2 additional information Bos taurus physiological role of enzyme ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.2 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.2 brain medium enzymic activity Bos taurus
-
3.1.4.2 kidney renal epithelial cell culture, low enzymic activity Bos taurus
-
3.1.4.2 liver medium enzymic activity Bos taurus
-
3.1.4.2 retina cultured retinal microcapillary pericytes, high enzymic activity Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.2 additional information physiological role of enzyme Bos taurus ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O
-
 Bos taurus sn-glycerol 3-phosphate + choline
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.4.2 8.5
-
-
 Bos taurus