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Literature summary extracted from

  • Barona-Gomez, F.; Hodgson, D.A.
    Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis (2003), EMBO Rep., 4, 296-300.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.3.1.16 the gene complements both hisA and trpF mutants of Escherichia coli Mycobacterium tuberculosis
5.3.1.16 the gene complements both hisA and trpF mutants of Escherichia coli Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.1.16 additional information Mycobacterium tuberculosis bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 has a dual function in both histidine and aromatic amino acid biosynthesis ?
-
 ?
5.3.1.16 additional information Streptomyces coelicolor bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 has a dual function in both histidine and aromatic amino acid biosynthesis ?
-
 ?
5.3.1.16 additional information Mycobacterium tuberculosis HR37Rv bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 has a dual function in both histidine and aromatic amino acid biosynthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.1.16 Mycobacterium tuberculosis
-
 HR37Rv
-
5.3.1.16 Mycobacterium tuberculosis HR37Rv
-
 HR37Rv
-
5.3.1.16 Streptomyces coelicolor
-
 A3
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.1.16 additional information bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 Mycobacterium tuberculosis ?
-
 ?
5.3.1.16 additional information bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 Streptomyces coelicolor ?
-
 ?
5.3.1.16 additional information bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 has a dual function in both histidine and aromatic amino acid biosynthesis Mycobacterium tuberculosis ?
-
 ?
5.3.1.16 additional information bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 has a dual function in both histidine and aromatic amino acid biosynthesis Streptomyces coelicolor ?
-
 ?
5.3.1.16 additional information bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 Mycobacterium tuberculosis HR37Rv ?
-
 ?
5.3.1.16 additional information bifunctional enzyme with activity of EC 5.3.1.16 and EC 5.3.1.24 has a dual function in both histidine and aromatic amino acid biosynthesis Mycobacterium tuberculosis HR37Rv ?
-
 ?