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Literature summary extracted from

  • Delbaere, L.T.J.; Sudom, A.M.; Prasad, L.; Leduc, Y.; Goldie, H.
    Structure/function studies of phosphoryl transfer by phosphoenolpyruvate carboxykinase (2004), Biochim. Biophys. Acta, 1697, 271-278.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.49
-
 Corynebacterium glutamicum

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.1.1.49
-
 Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.49 oxalate competitive inhibitor Corynebacterium glutamicum
4.1.1.49 oxalate competitive inhibitor Escherichia coli
4.1.1.49 oxalate competitive inhibitor Trypanosoma cruzi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.49 ATP + oxaloacetate Escherichia coli first commmitted step of gluconeogenesis ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate Corynebacterium glutamicum first commmitted step of gluconeogenesis ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate Trypanosoma cruzi first commmitted step of gluconeogenesis ADP + phosphoenolpyruvate + CO2
-
 r

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.49 Corynebacterium glutamicum
-
-
-
4.1.1.49 Escherichia coli
-
-
-
4.1.1.49 Trypanosoma cruzi
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.49 ATP + oxaloacetate
-
 Escherichia coli ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate
-
 Corynebacterium glutamicum ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate
-
 Trypanosoma cruzi ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate first commmitted step of gluconeogenesis Escherichia coli ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate first commmitted step of gluconeogenesis Corynebacterium glutamicum ADP + phosphoenolpyruvate + CO2
-
 r
4.1.1.49 ATP + oxaloacetate first commmitted step of gluconeogenesis Trypanosoma cruzi ADP + phosphoenolpyruvate + CO2
-
 r

Synonyms

EC Number Synonyms Comment Organism
4.1.1.49 ATP-oxaloacetate carboxylase (transphosphorylating)
-
 Escherichia coli
4.1.1.49 ATP-oxaloacetate carboxylase (transphosphorylating)
-
 Corynebacterium glutamicum
4.1.1.49 ATP-oxaloacetate carboxylase (transphosphorylating)
-
 Trypanosoma cruzi
4.1.1.49 PCK
-
 Escherichia coli
4.1.1.49 PCK
-
 Corynebacterium glutamicum
4.1.1.49 PCK
-
 Trypanosoma cruzi
4.1.1.49 phosphoenolpyruvate carboxykinase
-
 Escherichia coli
4.1.1.49 phosphoenolpyruvate carboxykinase
-
 Corynebacterium glutamicum
4.1.1.49 phosphoenolpyruvate carboxykinase
-
 Trypanosoma cruzi