Literature summary extracted from
Janosik, M.; Meier, M.; Kery, V.; Oliveriusova, J.; Burkhard, P.; Kraus, J.P.
Crystallization and preliminary x-ray diffraction analysis of the active core of human recombinant cystathionine beta-synthase: an enzyme involved in vascular disease (2001), Acta Crystallogr. Sect. D, D57, 289-291.
Application
EC Number |
Application |
Comment |
Organism |
---|
4.2.1.22 |
medicine |
inherited deficiency leads to homocystinuria, an autosomal recessivlely inherited disease of sulfur metabolism |
Homo sapiens |
Cloned(Commentary)
EC Number |
Cloned (Comment) |
Organism |
---|
4.2.1.22 |
truncated form fused with glutathione S-transferase |
Homo sapiens |
Crystallization (Commentary)
EC Number |
Crystallization (Comment) |
Organism |
---|
4.2.1.22 |
with heme and pyridoxal 5'-phosphate, hanging drop vapor diffusion method |
Homo sapiens |
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
4.2.1.22 |
Homo sapiens |
- |
- |
- |
Purification (Commentary)
EC Number |
Purification (Comment) |
Organism |
---|
4.2.1.22 |
- |
Homo sapiens |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
4.2.1.22 |
L-Serine + homocysteine |
- |
Homo sapiens |
Cystathionine + H2O |
- |
? |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
4.2.1.22 |
dimer |
truncated form of the enzyme |
Homo sapiens |
4.2.1.22 |
oligomer |
full length subunits for tetramers and higher oligomers |
Homo sapiens |
4.2.1.22 |
tetramer |
full length subunits for tetramers and higher oligomers |
Homo sapiens |