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Literature summary extracted from

  • Skern, T.; Liebig, H.D.
    Picornains 2A and 3C (1994), Methods Enzymol., 244, 583-595.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.28 expressed in Escherichia coli or BL21(D3) Enterovirus C
3.4.22.28 expressed in HeLa cells Foot-and-mouth disease virus
3.4.22.28 expressed in HeLa cells Enterovirus C
3.4.22.28 expressed in HeLa cells Encephalomyocarditis virus
3.4.22.28 expressed in HeLa cells enterovirus
3.4.22.28 expressed in HeLa cells Hepatovirus A
3.4.22.28 expressed in HeLa cells coxsackievirus
3.4.22.28 expressed in HeLa cells echovirus
3.4.22.28 expressed in HeLa cells Mengo virus
3.4.22.28 expressed in HeLa cells Theiler's encephalomyelitis virus
3.4.22.28 expressed in HeLa cells picornaviridae
3.4.22.29 expressed in HeLa cells Enterovirus C
3.4.22.29 expressed in HeLa cells enterovirus
3.4.22.29 expressed in HeLa cells coxsackievirus
3.4.22.29 expressed in HeLa cells picornaviridae
3.4.22.29 expressed in HeLa cells Human rhinovirus sp.

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.28 chymostatin
-
 enterovirus
3.4.22.28 Elastinal
-
 enterovirus
3.4.22.28 Hg2+
-
 coxsackievirus
3.4.22.28 Hg2+
-
 echovirus
3.4.22.28 Hg2+
-
 Encephalomyocarditis virus
3.4.22.28 Hg2+
-
 enterovirus
3.4.22.28 Hg2+
-
 Enterovirus C
3.4.22.28 Hg2+
-
 Foot-and-mouth disease virus
3.4.22.28 Hg2+
-
 Hepatovirus A
3.4.22.28 Hg2+
-
 Mengo virus
3.4.22.28 Hg2+
-
 picornaviridae
3.4.22.28 Hg2+
-
 Theiler's encephalomyelitis virus
3.4.22.28 iodoacetamide
-
 coxsackievirus
3.4.22.28 iodoacetamide
-
 echovirus
3.4.22.28 iodoacetamide
-
 Encephalomyocarditis virus
3.4.22.28 iodoacetamide
-
 enterovirus
3.4.22.28 iodoacetamide
-
 Enterovirus C
3.4.22.28 iodoacetamide
-
 Foot-and-mouth disease virus
3.4.22.28 iodoacetamide
-
 Hepatovirus A
3.4.22.28 iodoacetamide
-
 Mengo virus
3.4.22.28 iodoacetamide
-
 picornaviridae
3.4.22.28 iodoacetamide
-
 Theiler's encephalomyelitis virus
3.4.22.28 additional information no inhibition by Triton X-100, that inhibits picornain 3CD enterovirus
3.4.22.28 additional information
-
 Enterovirus C
3.4.22.28 NEM
-
 coxsackievirus
3.4.22.28 NEM
-
 echovirus
3.4.22.28 NEM
-
 Encephalomyocarditis virus
3.4.22.28 NEM
-
 enterovirus
3.4.22.28 NEM
-
 Enterovirus C
3.4.22.28 NEM
-
 Foot-and-mouth disease virus
3.4.22.28 NEM
-
 Hepatovirus A
3.4.22.28 NEM
-
 Mengo virus
3.4.22.28 NEM
-
 picornaviridae
3.4.22.28 NEM
-
 Theiler's encephalomyelitis virus
3.4.22.29 chymostatin
-
 coxsackievirus
3.4.22.29 chymostatin
-
 enterovirus
3.4.22.29 chymostatin
-
 Enterovirus C
3.4.22.29 chymostatin
-
 Human rhinovirus sp.
3.4.22.29 chymostatin
-
 picornaviridae
3.4.22.29 Elastinal
-
 coxsackievirus
3.4.22.29 Elastinal
-
 enterovirus
3.4.22.29 Elastinal
-
 Enterovirus C
3.4.22.29 Elastinal
-
 Human rhinovirus sp.
3.4.22.29 Elastinal
-
 picornaviridae
3.4.22.29 Hg2+
-
 coxsackievirus
3.4.22.29 Hg2+
-
 enterovirus
3.4.22.29 Hg2+
-
 Enterovirus C
3.4.22.29 Hg2+
-
 Human rhinovirus sp.
3.4.22.29 Hg2+
-
 picornaviridae
3.4.22.29 iodoacetamide
-
 coxsackievirus
3.4.22.29 iodoacetamide
-
 enterovirus
3.4.22.29 iodoacetamide
-
 Enterovirus C
3.4.22.29 iodoacetamide
-
 Human rhinovirus sp.
3.4.22.29 iodoacetamide
-
 picornaviridae
3.4.22.29 additional information no inhibition by trans-epoxysuccinyl-L-leucylamido(4-guanidino)-butane (i.e. E-64) coxsackievirus
3.4.22.29 additional information no inhibition by trans-epoxysuccinyl-L-leucylamido(4-guanidino)-butane (i.e. E-64) enterovirus
3.4.22.29 additional information no inhibition by trans-epoxysuccinyl-L-leucylamido(4-guanidino)-butane (i.e. E-64) Enterovirus C
3.4.22.29 additional information no inhibition by trans-epoxysuccinyl-L-leucylamido(4-guanidino)-butane (i.e. E-64) Human rhinovirus sp.
3.4.22.29 additional information no inhibition by trans-epoxysuccinyl-L-leucylamido(4-guanidino)-butane (i.e. E-64) picornaviridae
3.4.22.29 NEM
-
 coxsackievirus
3.4.22.29 NEM
-
 enterovirus
3.4.22.29 NEM
-
 Enterovirus C
3.4.22.29 NEM
-
 Human rhinovirus sp.
3.4.22.29 NEM
-
 picornaviridae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.22.28 0.25 2.6 peptides derived from polyprotein cleavage sites
-
 enterovirus
3.4.22.29 0.5
-
 Thr-Arg-Pro-Ile-Ile-Thr-Thr-Ala-Gly-Pro-Ser-Asp-Met-Val-Tyr human rhinovirus Human rhinovirus sp.

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.28 membrane recombinant enzyme Foot-and-mouth disease virus 16020
-
3.4.22.28 membrane recombinant enzyme Enterovirus C 16020
-
3.4.22.28 membrane recombinant enzyme Encephalomyocarditis virus 16020
-
3.4.22.28 membrane recombinant enzyme enterovirus 16020
-
3.4.22.28 membrane recombinant enzyme Hepatovirus A 16020
-
3.4.22.28 membrane recombinant enzyme coxsackievirus 16020
-
3.4.22.28 membrane recombinant enzyme echovirus 16020
-
3.4.22.28 membrane recombinant enzyme Mengo virus 16020
-
3.4.22.28 membrane recombinant enzyme Theiler's encephalomyelitis virus 16020
-
3.4.22.28 membrane recombinant enzyme picornaviridae 16020
-
3.4.22.28 membrane rhinovirus, expressed in Escherichia coli enterovirus 16020
-
3.4.22.28 soluble recombinant enzyme Foot-and-mouth disease virus
-
-
3.4.22.28 soluble recombinant enzyme Enterovirus C
-
-
3.4.22.28 soluble recombinant enzyme Encephalomyocarditis virus
-
-
3.4.22.28 soluble recombinant enzyme enterovirus
-
-
3.4.22.28 soluble recombinant enzyme Hepatovirus A
-
-
3.4.22.28 soluble recombinant enzyme coxsackievirus
-
-
3.4.22.28 soluble recombinant enzyme echovirus
-
-
3.4.22.28 soluble recombinant enzyme Mengo virus
-
-
3.4.22.28 soluble recombinant enzyme Theiler's encephalomyelitis virus
-
-
3.4.22.28 soluble recombinant enzyme picornaviridae
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.29 additional information
-
 Enterovirus C
3.4.22.29 additional information
-
 enterovirus
3.4.22.29 additional information
-
 coxsackievirus
3.4.22.29 additional information
-
 picornaviridae
3.4.22.29 additional information human rhinovirus HRV 2 enzyme is largely unaffected by ionic strength Human rhinovirus sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.29 17000
-
-
 Human rhinovirus sp.
3.4.22.29 17000
-
 coxsackievirus B4, gel filtration coxsackievirus
3.4.22.29 30000
-
 human rhinovirus HRV 2, gel filtration Human rhinovirus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.28 activated transcription factor TFIIIC + H2O Enterovirus C in HeLa-cells, poliovirus enzyme, involved in shut-off of host-cell transcription ?
-
 ?
3.4.22.28 picornavirus polyprotein + H2O Foot-and-mouth disease virus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O Enterovirus C involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O Encephalomyocarditis virus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O enterovirus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O Hepatovirus A involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O coxsackievirus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O echovirus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O Mengo virus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O Theiler's encephalomyelitis virus involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O picornaviridae involved in proteolytic processing of virus polyprotein hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O picornaviridae intramolecular reaction, processing begins before synthesis of the polyprotein is complete, cleavage separates capsid protein precursor and noncapsid protein precursor ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.28 coxsackievirus
-
-
-
3.4.22.28 echovirus
-
-
-
3.4.22.28 Encephalomyocarditis virus
-
-
-
3.4.22.28 enterovirus
-
 human rhinovirus
-
3.4.22.28 Enterovirus C
-
-
-
3.4.22.28 Foot-and-mouth disease virus
-
-
-
3.4.22.28 Hepatovirus A
-
-
-
3.4.22.28 Mengo virus
-
-
-
3.4.22.28 picornaviridae
-
 overview
-
3.4.22.28 Theiler's encephalomyelitis virus
-
-
-
3.4.22.29 coxsackievirus
-
 B4
-
3.4.22.29 enterovirus
-
 bovine enterovirus
-
3.4.22.29 Enterovirus C
-
-
-
3.4.22.29 Human rhinovirus sp.
-
 serotypes 2
-
3.4.22.29 Human rhinovirus sp.
-
 serotypes 2 (HRV 2)
-
3.4.22.29 picornaviridae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.28 as expressed in Escherichia coli enterovirus
3.4.22.28 from Escherichia coli membrane fraction enterovirus
3.4.22.28 recombinant enzyme Enterovirus C
3.4.22.28 recombinant enzyme from Escherichia coli in soluble form Enterovirus C
3.4.22.28 recombinant enzyme from infected HeLa cells, to near homogeneity Enterovirus C
3.4.22.29 as a fusion protein coxsackievirus
3.4.22.29 from infected HeLa cells Enterovirus C
3.4.22.29 HRV 2 Human rhinovirus sp.
3.4.22.29 recombinant enzyme as fusion protein Human rhinovirus sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.29 additional information synthesized in cells following infection by picornaviruses Enterovirus C
-
3.4.22.29 additional information synthesized in cells following infection by picornaviruses enterovirus
-
3.4.22.29 additional information synthesized in cells following infection by picornaviruses coxsackievirus
-
3.4.22.29 additional information synthesized in cells following infection by picornaviruses picornaviridae
-
3.4.22.29 additional information synthesized in cells following infection by picornaviruses Human rhinovirus sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.28 activated transcription factor TFIIIC + H2O in HeLa-cells, poliovirus enzyme Enterovirus C ?
-
 ?
3.4.22.28 activated transcription factor TFIIIC + H2O in HeLa-cells, poliovirus enzyme, involved in shut-off of host-cell transcription Enterovirus C ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 Foot-and-mouth disease virus ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 Enterovirus C ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 Encephalomyocarditis virus ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 Hepatovirus A ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 coxsackievirus ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 echovirus ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 Mengo virus ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 Theiler's encephalomyelitis virus ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O
-
 picornaviridae ?
-
 ?
3.4.22.28 cardiovirus polyprotein + H2O cleavage specificity enterovirus ?
-
 ?
3.4.22.28 encephalomyocarditis virus polyprotein + H2O cleavage sites: Gln-Gly, Glu-Ser and Glu-Ala Encephalomyocarditis virus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 Foot-and-mouth disease virus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 Enterovirus C ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 Encephalomyocarditis virus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 Hepatovirus A ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 coxsackievirus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 echovirus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 Mengo virus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 Theiler's encephalomyelitis virus ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O
-
 picornaviridae ?
-
 ?
3.4.22.28 enterovirus polyprotein + H2O cleavage specificity enterovirus ?
-
 ?
3.4.22.28 histone protein H3 + H2O in BHK-cells, foot-and-mouth-disease virus enzyme Foot-and-mouth disease virus ?
-
 ?
3.4.22.28 peptides derived from polyprotein cleavage sites + H2O
-
 enterovirus ?
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 Foot-and-mouth disease virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 Enterovirus C hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 Encephalomyocarditis virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 enterovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 Hepatovirus A hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 coxsackievirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 echovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 Mengo virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 Theiler's encephalomyelitis virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O
-
 picornaviridae hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein Foot-and-mouth disease virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein Enterovirus C hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein Encephalomyocarditis virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein enterovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein Hepatovirus A hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein coxsackievirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein echovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein Mengo virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein Theiler's encephalomyelitis virus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 picornavirus polyprotein + H2O involved in proteolytic processing of virus polyprotein picornaviridae hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.28 poliovirus polyprotein + H2O initial cleavage at 2C-3A and 2B-2C, followed by 3A-3B and/or 3C-3D Enterovirus C hydrolyzed poliovirus polyprotein
-
 ?
3.4.22.28 rhinovirus polyprotein + H2O cleavage specificity enterovirus ?
-
 ?
3.4.22.29 additional information cleavage specificity Enterovirus C ?
-
 ?
3.4.22.29 additional information cleavage specificity enterovirus ?
-
 ?
3.4.22.29 additional information cleavage specificity coxsackievirus ?
-
 ?
3.4.22.29 additional information cleavage specificity picornaviridae ?
-
 ?
3.4.22.29 additional information cleavage specificity Human rhinovirus sp. ?
-
 ?
3.4.22.29 additional information the primary cleavage in cardio- and aphthovirus occurs between 2A and 2B (cleavage site: Gly-Pro in-Asn-Pro-Gly-Pro-) Enterovirus C ?
-
 ?
3.4.22.29 additional information the primary cleavage in cardio- and aphthovirus occurs between 2A and 2B (cleavage site: Gly-Pro in-Asn-Pro-Gly-Pro-) enterovirus ?
-
 ?
3.4.22.29 additional information the primary cleavage in cardio- and aphthovirus occurs between 2A and 2B (cleavage site: Gly-Pro in-Asn-Pro-Gly-Pro-) coxsackievirus ?
-
 ?
3.4.22.29 additional information the primary cleavage in cardio- and aphthovirus occurs between 2A and 2B (cleavage site: Gly-Pro in-Asn-Pro-Gly-Pro-) picornaviridae ?
-
 ?
3.4.22.29 additional information the primary cleavage in cardio- and aphthovirus occurs between 2A and 2B (cleavage site: Gly-Pro in-Asn-Pro-Gly-Pro-) Human rhinovirus sp. ?
-
 ?
3.4.22.29 picornavirus polyprotein + H2O immediately after protease 2A has been synthesized the Tyr-Gly pair between P1 and P2 of the nascent rhinovirus or enterovirus chain is cleaved intramolecularly Enterovirus C hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O immediately after protease 2A has been synthesized the Tyr-Gly pair between P1 and P2 of the nascent rhinovirus or enterovirus chain is cleaved intramolecularly enterovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O immediately after protease 2A has been synthesized the Tyr-Gly pair between P1 and P2 of the nascent rhinovirus or enterovirus chain is cleaved intramolecularly coxsackievirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O immediately after protease 2A has been synthesized the Tyr-Gly pair between P1 and P2 of the nascent rhinovirus or enterovirus chain is cleaved intramolecularly picornaviridae hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O immediately after protease 2A has been synthesized the Tyr-Gly pair between P1 and P2 of the nascent rhinovirus or enterovirus chain is cleaved intramolecularly Human rhinovirus sp. hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleavage between C-terminus of VP1 and N-terminus of picornain 2A Enterovirus C hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleavage between C-terminus of VP1 and N-terminus of picornain 2A enterovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleavage between C-terminus of VP1 and N-terminus of picornain 2A coxsackievirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleavage between C-terminus of VP1 and N-terminus of picornain 2A picornaviridae hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleavage between C-terminus of VP1 and N-terminus of picornain 2A Human rhinovirus sp. hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleaves intermolecularly at a second site in the 3D protein between 3C' and 3D' Enterovirus C hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleaves intermolecularly at a second site in the 3D protein between 3C' and 3D' enterovirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleaves intermolecularly at a second site in the 3D protein between 3C' and 3D' coxsackievirus hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleaves intermolecularly at a second site in the 3D protein between 3C' and 3D' picornaviridae hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O cleaves intermolecularly at a second site in the 3D protein between 3C' and 3D' Human rhinovirus sp. hydrolyzed picornavirus polyprotein
-
 ?
3.4.22.29 picornavirus polyprotein + H2O intramolecular reaction, processing begins before synthesis of the polyprotein is complete, cleavage separates capsid protein precursor and noncapsid protein precursor picornaviridae ?
-
 ?
3.4.22.29 Thr-Arg-Pro-Ile-Ile-Thr-Thr-Ala-Gly-Pro-Ser-Asp-Met-Val-Tyr + H2O
-
 Human rhinovirus sp. ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.22.28 7 8
-
 Enterovirus C
3.4.22.28 7 8
-
 enterovirus
3.4.22.29 7 8
-
 Enterovirus C
3.4.22.29 7 8
-
 enterovirus
3.4.22.29 7 8
-
 coxsackievirus
3.4.22.29 7 8
-
 picornaviridae
3.4.22.29 7 8
-
 Human rhinovirus sp.