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Literature summary extracted from

  • Deguchi, A.; Segawa, K.; Hosaka, K.; Weinstein, I.B.; Umezawa, K.
    Overexpression of phosphatidylinositol synthase enhances growth and G1 progression in NIH3T3 cells (2002), Jpn. J. Cancer Res., 93, 157-166.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.11 rat PIS expressed in mouse NIH3T3 fibroblasts by transfection with a FLAG-tagged PIS cDNA using the vector pcDNA3 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.8.11 Inostamycin
-
 Mus musculus
2.7.8.11 Inostamycin
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.11 CDP-diacylglycerol + myo-inositol Mus musculus
-
 CMP + phosphatidyl-1D-myo-inositol
-
 r
2.7.8.11 CDP-diacylglycerol + myo-inositol Rattus norvegicus
-
 CMP + phosphatidyl-1D-myo-inositol
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.11 Mus musculus
-
 mouse
-
2.7.8.11 Rattus norvegicus
-
 rat
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.11 fibroblast NIH3T3 cells Mus musculus
-
2.7.8.11 NIH-3T3 cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.11 CDP-diacylglycerol + myo-inositol
-
 Mus musculus CMP + phosphatidyl-1D-myo-inositol
-
 r
2.7.8.11 CDP-diacylglycerol + myo-inositol
-
 Rattus norvegicus CMP + phosphatidyl-1D-myo-inositol
-
 r