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Literature summary extracted from

  • Ku, M.J.; Yoon, H.J.; Ahn, H.J.; Kim, H.W.; Baek, S.H.; Suh, S.W.
    Crystallization and preliminary X-ray crystallographic studies of 3-deoxy-manno-octulosonate cytidylyltransferase from Haemophilus influenzae (2003), Acta Crystallogr. Sect. D, 59, 180-182.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.7.7.38 medicine essential for the biosynthesis of lipopolysaccharides in gram-negative bacteria, potential target for the discovery of antibacterial agents Haemophilus influenzae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.38 overexpressed with a C-terminal hexahistidine tag in Escherichia coli Haemophilus influenzae

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.7.38 native crystals are orthorhombic, belonging to space group P2(1)2(1)2(1) with unit-cell parameters a = 48.6, b = 83.1, c = 117.3 A Haemophilus influenzae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.38 CTP + 3-deoxy-D-manno-octulosonate Haemophilus influenzae
-
 diphosphate + CMP-3-deoxy-D-manno-octulosonate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.38 Haemophilus influenzae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.38 CTP + 3-deoxy-D-manno-octulosonate
-
 Haemophilus influenzae diphosphate + CMP-3-deoxy-D-manno-octulosonate
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.7.7.38 L-CKS
-
 Haemophilus influenzae