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Literature summary extracted from

  • Caplow, M.; Shanks, J.
    Mechanism of the microtubule GTPase reaction (1990), J. Biol. Chem., 265, 8935-8941.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.5.6 GDP
-
 Bos taurus
3.6.5.6 GDP
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.6.5.6 55000
-
 SDS-PAGE Sus scrofa
3.6.5.6 101000
-
 1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit Sus scrofa
3.6.5.6 106000
-
 1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit Sus scrofa
3.6.5.6 115000
-
 1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit Sus scrofa
3.6.5.6 128000
-
 1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.5.6 GTP + H2O Sus scrofa
-
 GDP + phosphate
-
 ?
3.6.5.6 GTP + H2O Bos taurus
-
 GDP + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.5.6 Bos taurus
-
-
-
3.6.5.6 Sus scrofa
-
 pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.6.5.6
-
 Sus scrofa
3.6.5.6
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.6.5.6 brain
-
 Sus scrofa
-
3.6.5.6 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.5.6 GTP + H2O
-
 Sus scrofa GDP + phosphate
-
 ?
3.6.5.6 GTP + H2O
-
 Bos taurus GDP + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.5.6 tetramer 1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit Sus scrofa