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Literature summary extracted from

  • Bowman, C.M.; Valdez, R.O.; Nishimura, J.S.
    Acetate kinase from Veillonella alcalescens. Regulation of enzyme activity by succinate and substrates (1976), J. Biol. Chem., 251, 3117-3121.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.2.1 succinate heterotropic allosteric effector, necessary for enzymatic activity in both directions Veillonella parvula

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.2.1 1.1
-
 ADP pH 7.3, 37°C, 1.0 M succinate Veillonella parvula
2.7.2.1 1.3
-
 ADP pH 7.3, 37°C, 0.2 M succinate Veillonella parvula
2.7.2.1 3.3
-
 acetyl phosphate pH 7.3, 37°C, 2.0 M succinate Veillonella parvula
2.7.2.1 5
-
 acetyl phosphate pH 7.3, 37°C, 0.2 M succinate Veillonella parvula
2.7.2.1 9
-
 ATP pH 7.3, 37°C, 50 M succinate Veillonella parvula
2.7.2.1 10
-
 ATP pH 7.3, 37°C, 5.0 M succinate Veillonella parvula
2.7.2.1 100
-
 acetate pH 7.3, 37°C, 50 M succinate Veillonella parvula
2.7.2.1 170
-
 acetate pH 7.3, 37°C, 5.0 M succinate Veillonella parvula
2.7.2.1 300
-
 propionate pH 7.3, 37°C, 50 M succinate Veillonella parvula
2.7.2.1 1000
-
 propionate pH 7.3, 37°C, 5.0 M succinate Veillonella parvula

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.2.1 44000
-
 2 * 44000, SDS-PAGE Veillonella parvula
2.7.2.1 87000
-
 gel filtration Veillonella parvula

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.2.1 ATP + acetate Veillonella parvula
-
 ADP + acetyl phosphate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.1 Veillonella parvula
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.2.1 375 500
-
 Veillonella parvula

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.1 ATP + acetate
-
 Veillonella parvula ADP + acetyl phosphate
-
 r
2.7.2.1 ATP + propionate
-
 Veillonella parvula ADP + propionyl phosphate
-
 r

Subunits

EC Number Subunits Comment Organism
2.7.2.1 dimer 2 * 44000, SDS-PAGE Veillonella parvula