EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.18 | 3-Hydroxyanthranilate | competitive | Ogataea henricii | |
2.4.2.18 | anthranilate | substrate inhibition above 0.008 mM | Ogataea henricii |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.18 | 0.0046 | - |
anthranilate | - |
Ogataea henricii | |
2.4.2.18 | 0.88 | - |
5-phospho-alpha-D-ribose 1-diphosphate | - |
Ogataea henricii |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.18 | Mg2+ | activates | Ogataea henricii | |
2.4.2.18 | Mg2+ | Km: 0.056 mM | Ogataea henricii |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.4.2.18 | 70000 | - |
gel filtration | Ogataea henricii |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | Ogataea henricii | enzyme of tryptophan biosynthesis | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.18 | Ogataea henricii | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.2.18 | - |
Ogataea henricii |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.4.2.18 | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | reaction mechanism | Ogataea henricii |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.4.2.18 | 0.4 | - |
- |
Ogataea henricii |
EC Number | Storage Stability | Organism |
---|---|---|
2.4.2.18 | -25°C, 500 mM Tris-HCl, pH 7.5, 2 mM EDTA, 2 mM MgCl2, 5% loss of activity after 2 weeks | Ogataea henricii |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Ogataea henricii | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
? | |
2.4.2.18 | anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate | enzyme of tryptophan biosynthesis | Ogataea henricii | N-(5-phospho-D-ribosyl)-anthranilate + diphosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.4.2.18 | More | no aggregation with other enzymes | Ogataea henricii |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.4.2.18 | 37 | - |
assay at | Ogataea henricii |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.2.18 | 7.4 | 7.7 | - |
Ogataea henricii |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.18 | 0.012 | - |
3-Hydroxyanthranilate | - |
Ogataea henricii | |
2.4.2.18 | 0.03 | - |
anthranilate | - |
Ogataea henricii |