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Literature summary extracted from

  • Datti, A.; Dennis, J.W.
    Regulation of UDP-GlcNAc:Galbeta1-3GalNAc-R beta1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in chinese hamster ovary cells (1993), J. Biol. Chem., 268, 5409-5416.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.102 additional information no effect of dimethyl sulfoxide, retinoic acid, phorbol ester, cholera toxin Cricetulus griseus
2.4.1.102 sodium butyrate induction after treatment of cells for 24 h, 16fold increase in activity, blocked by actinomycin D and cycloheximide Cricetulus griseus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.102 additional information no effect of dimethyl sulfoxide, retinoic acid, phorbol ester, cholera toxin Cricetulus griseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.102 0.5
-
 UDP-N-acetyl-D-glucosamine
-
 Cricetulus griseus
2.4.1.102 4.54
-
 UDP-N-acetyl-D-glucosamine butyrate treated cells Cricetulus griseus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.102 Cricetulus griseus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.102 CHO cell
-
 Cricetulus griseus
-
2.4.1.102 ovary
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.102 UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R
-
 Cricetulus griseus UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R i.e. core class 2 ?
2.4.1.102 UDP-N-acetyl-D-glucosamine + galactosyl-beta-1,3-N-acetyl-beta-D-glucosaminyl-p-nitrophenyl
-
 Cricetulus griseus UDP + galactosyl-beta-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-beta-D-glucosaminyl-p-nitrophenyl
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.102 core 2 GlcNAc-T
-
 Cricetulus griseus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.102 37
-
 assay at Cricetulus griseus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.102 7.4
-
 assay at Cricetulus griseus