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Literature summary extracted from

  • Vereb, G.; Fodor, A.; Bot, G.
    Kinetic characterization of rabbit skeletal muscle phosphorylase ab hybrid (1987), Biochim. Biophys. Acta, 915, 19-27.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.1 5'-AMP activation Oryctolagus cuniculus
2.4.1.1 IMP 0.1 mM, half-maximal activation of phosphorylase ab Oryctolagus cuniculus
2.4.1.1 phosphate activation Oryctolagus cuniculus
2.4.1.1 Phosphorylase kinase activation Oryctolagus cuniculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.1 D-glucose 5 mM and 8.5 mM, 50% inhibition of phosphorylase ab at 8 mM and 16 mM glucose 1-phosphate, 23 mM and 40 mM, 50% inhibition of phosphorylase a Oryctolagus cuniculus
2.4.1.1 glucose 6-phosphate
-
 Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.1 additional information
-
 additional information kinetic data Oryctolagus cuniculus
2.4.1.1 3.56
-
 glucose 1-phosphate phosphorylase a Oryctolagus cuniculus
2.4.1.1 18
-
 glucose 1-phosphate phosphorylase ab Oryctolagus cuniculus
2.4.1.1 20
-
 glucose 1-phosphate phosphorylase ab Oryctolagus cuniculus
2.4.1.1 28
-
 phosphate phosphorylase ab Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.1 Oryctolagus cuniculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.1 side-chain modification activation by phosphorylation Oryctolagus cuniculus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.1 phosphorylase ab hybrid Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.1 muscle skeletal muscle Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.1 glycogen + glucose 1-phosphate
-
 Oryctolagus cuniculus glycogen + phosphate
-
 r
2.4.1.1 [(1->4)-alpha-D-glucosyl]n + phosphate
-
 Oryctolagus cuniculus [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate
-
 r

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.1 1.5
-
 glucose 6-phosphate phosphorylase ab Oryctolagus cuniculus
2.4.1.1 4.5
-
 glucose phosphorylase ab and a Oryctolagus cuniculus