EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.3.16 | 2-oxoglutarate | competitive against oxaloacetate | Drosophila melanogaster | |
2.3.3.16 | ATP | competitive against acetyl-CoA | Drosophila melanogaster | |
2.3.3.16 | additional information | tricarboxylic acid cycle intermediates | Drosophila melanogaster | |
2.3.3.16 | propionyl-CoA | competitive against acetyl-CoA | Drosophila melanogaster | |
2.3.3.16 | succinyl-CoA | mixed-type inhibition | Drosophila melanogaster |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.3.16 | 0.0031 | - |
oxaloacetate | - |
Drosophila melanogaster | |
2.3.3.16 | 0.0067 | - |
acetyl-CoA | - |
Drosophila melanogaster |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.3.16 | additional information | - |
amino acid composition | Drosophila melanogaster |
2.3.3.16 | 48700 | - |
2 * 48700, SDS-PAGE | Drosophila melanogaster |
2.3.3.16 | 81000 | - |
gel filtration | Drosophila melanogaster |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.3.16 | Drosophila melanogaster | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.3.16 | antibody studies | Drosophila melanogaster |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.3.3.16 | acetyl-CoA + H2O + oxaloacetate = citrate + CoA | mechanism | Drosophila melanogaster |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.3.3.16 | 112.5 | - |
purified enzyme | Drosophila melanogaster |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.3.16 | acetyl-CoA + oxaloacetate + H2O | - |
Drosophila melanogaster | citrate + CoA | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.3.16 | dimer | 2 * 48700, SDS-PAGE | Drosophila melanogaster |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.3.3.16 | 45 | - |
- |
Drosophila melanogaster |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.3.16 | 8 | 9 | - |
Drosophila melanogaster |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.3.16 | 0.0024 | - |
propionyl-CoA | versus acetyl-CoA, competitive | Drosophila melanogaster | |
2.3.3.16 | 0.0225 | - |
propionyl-CoA | versus oxaloacetate, noncompetitive | Drosophila melanogaster | |
2.3.3.16 | 0.125 | - |
ATP | versus acetyl-CoA | Drosophila melanogaster | |
2.3.3.16 | 0.38 | - |
2-oxoglutarate | versus oxaloacetate, competitive | Drosophila melanogaster |