EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.57 | additional information | enzyme is induced by isopropyl beta-D-thiogalactopyranoside | Homo sapiens |
EC Number | Application | Comment | Organism |
---|---|---|---|
2.3.1.57 | medicine | the ability of polyamine analogues to induce N1SSAT activity correlates with the ability to inhibit growth and viability of human tumor-derived cells | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.57 | cloning and conditional expression of cDNA encoding enzyme in Escherichia coli CAG2242 results in a decrease of endogenous spermidine contents and growth rates | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.57 | acetyl-CoA + spermidine | Homo sapiens | spermidine acetylation might be a strategy for inhibiting growth in response to environmental stresses | CoA + N1-acetylspermidine | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.57 | Homo sapiens | - |
recombinant enzyme, expressed in Escherichia coli CAG2242 | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.57 | acetyl-CoA + spermidine | - |
Homo sapiens | CoA + N1-acetylspermidine | product is exclusively N1-acetylspermidine | ? | |
2.3.1.57 | acetyl-CoA + spermidine | spermidine acetylation might be a strategy for inhibiting growth in response to environmental stresses | Homo sapiens | CoA + N1-acetylspermidine | - |
? | |
2.3.1.57 | acetyl-CoA + spermine | - |
Homo sapiens | CoA + N1-acetylspermine | - |
? |