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Literature summary extracted from

  • Garnepudi, V.R.; Zhao, C.; Beeler, T.; Dunn, T.
    Serine palmitoyltransferase (scs1/lcb2) mutants have elevated copy number of the L-A dsRNA virus (1997), Yeast, 13, 299-304.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.50 additional information natural mutant strains: SCS1/LCB2 knock-out mutant, scs1-1 mutant shows reduced activity, scs1-2 mutant is temperature-sensitive, but shows normal enzyme activity Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.50 microsome microsome isolation from mutant strains Saccharomyces cerevisiae
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.50 90000
-
 x * 90000, SDS-PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.50 palmitoyl-CoA + L-serine Saccharomyces cerevisiae
-
 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.50 Saccharomyces cerevisiae
-
 gene LCB1/SCS1
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.50 palmitoyl-CoA + L-serine
-
 Saccharomyces cerevisiae CoA + 3-dehydro-D-sphinganine + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.50 ? x * 90000, SDS-PAGE Saccharomyces cerevisiae

Synonyms

EC Number Synonyms Comment Organism
2.3.1.50 More the amount of enzyme activity in microsomes is inversely correlated with the amount of the major coat Gag protein of the L-A dsRNA virus particles Saccharomyces cerevisiae