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Literature summary extracted from

  • Shen, Y.; Tiralongo, J.; Iwersen, M.; Sipos, B.; Kalthoff, H.; Schauer, R.
    Characterization of the sialate-7(9)-O-acetyltransferase from the microsomes of human colonic mucosa (2002), Biol. Chem., 383, 307-317.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.45 CoA
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.45 0.0061
-
 acetyl-CoA
-
 Homo sapiens
2.3.1.45 0.059
-
 CMP-5-N-acetyl-neuraminate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.45 cytosol not Homo sapiens 5829
-
2.3.1.45 Golgi vesicle
-
 Homo sapiens
-
-
2.3.1.45 microsome
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.45 acetyl-CoA + sialic acid Homo sapiens
-
 CoA + N-acetyl-7-O(or 9-O-)-acetylneuraminate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.45 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.45 colon mucosa Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.45 acetyl-CoA + alpha-2,3-sialyllactose
-
 Homo sapiens ?
-
 ?
2.3.1.45 acetyl-CoA + alpha-2,6-sialyllactose
-
 Homo sapiens ?
-
 ?
2.3.1.45 acetyl-CoA + CMP-5-N-acetylneuraminate
-
 Homo sapiens CoA + CMP-5-N-acetyl-9-O-acetyl-neuraminate
-
 ?
2.3.1.45 acetyl-CoA + CMP-N-acetyl-neuraminate
-
 Homo sapiens CoA + CMP-9-O-acetyl-N-acetylneuraminate
-
 ?
2.3.1.45 acetyl-CoA + N-acetylneuraminate
-
 Homo sapiens CoA + N-acetyl-7-O(or 9-O-)-acetylneuraminate
-
 ?
2.3.1.45 acetyl-CoA + sialic acid
-
 Homo sapiens CoA + N-acetyl-7-O(or 9-O-)-acetylneuraminate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.45 sialate-7(9)-O-acetyltransferase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.45 37
-
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.45 7
-
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.45 0.0119
-
 CoA
-
 Homo sapiens