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Literature summary extracted from

  • Ofman, R.; Wanders, R.J.A.
    Purification of peroxisomal acyl-CoA:dihydroxyacetonephosphate acyltransferase from human placenta (1994), Biochim. Biophys. Acta, 1206, 27-34.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.42 additional information enzyme amount is reduced by 90% in Zellweger syndrome Homo sapiens

General Stability

EC Number General Stability Organism
2.3.1.42 dipalmitoylphosphatidylcholine stabilizes purified enzyme Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.42 peroxisome
-
 Homo sapiens 5777
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.42 60000 80000 gel filtration Homo sapiens
2.3.1.42 65000
-
 1 * 65000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.42 additional information Homo sapiens enzyme amount is reduced by 90% in Zellweger syndrome ?
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate Homo sapiens
-
 CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.42 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.42 peroxisomal from placenta, with 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, i.e. CHAPS, plus 1 M KCl Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.42 liver
-
 Homo sapiens
-
2.3.1.42 placenta
-
 Homo sapiens
-
2.3.1.42 skin fibroblast
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.42 0.00061
-
 purified enzyme Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate
-
 Homo sapiens CoA + acyldihydroxyacetone phosphate
-
 ?
2.3.1.42 cis-9-hexadecenoyl-CoA + dihydroxyacetone phosphate
-
 Homo sapiens CoA + cis-9-hexadecenoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 additional information enzyme amount is reduced by 90% in Zellweger syndrome Homo sapiens ?
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate
-
 Homo sapiens CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate best substrate Homo sapiens CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 tetradecanoyl-CoA + dihydroxyacetone phosphate i.e. myristoyl-CoA Homo sapiens CoA + tetradecanoyldihydroxyacetone phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.42 monomer 1 * 65000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.3.1.42 DHAPAT
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.42 37
-
 assay at Homo sapiens