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Literature summary extracted from

  • Miyazawa, S.; Ozaka, H.; Osumi, T.; Hashiomoto, T.
    Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver (1983), J. Biochem., 94, 529-542.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.21 di(2-ethyl-hexyl)phtalate
-
 Rattus norvegicus

General Stability

EC Number General Stability Organism
2.3.1.21 quite stable at all steps of purification Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 2-bromopalmitoyl-CoA no inhibition Rattus norvegicus
2.3.1.21 malonyl-CoA
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 additional information
-
 additional information
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 membrane
-
 Rattus norvegicus 16020
-
2.3.1.21 mitochondrion
-
 Rattus norvegicus 5739
-
2.3.1.21 nucleus
-
 Rattus norvegicus 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 69200
-
 x * 69200, SDS-PAGE Rattus norvegicus
2.3.1.21 280000 320000 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.21
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.21 29.6
-
 purified enzyme Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
2.3.1.21 -20°C, several months Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 r
2.3.1.21 acyl-CoA + L-carnitine substrate specificity Rattus norvegicus CoA + L-acylcarnitine
-
 r
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-palmitoylcarnitine
-
 r

Subunits

EC Number Subunits Comment Organism
2.3.1.21 ? x * 69200, SDS-PAGE Rattus norvegicus