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Literature summary extracted from

  • Ramsay, R.R.
    The soluble carnitine palmitoyltransferase from bovine liver. A comparison with the enzymes from peroxisomes and from the mitochondrial inner membrane (1988), Biochem. J., 249, 239-245.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 malonyl-CoA inhibition of soluble peroxisomal form, no inhibition of enzyme from inner mitochondrial membrane Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 0.17
-
 L-carnitine peroxisomal soluble enzyme Bos taurus
2.3.1.21 2.8
-
 L-carnitine inner mitochondrial membrane Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 cytosol peroxisomal, liver Bos taurus 5829
-
2.3.1.21 mitochondrion
-
 Bos taurus 5739
-
2.3.1.21 peroxisome
-
 Bos taurus 5777
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 67000
-
 x * 67000, SDS-PAGE Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Bos taurus
-
 CoA + L-acylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Bos taurus
-
 2 enzyme forms: inner membrane enzyme in mitochondria and soluble enzyme from peroxisomes
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 heart
-
 Bos taurus
-
2.3.1.21 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Bos taurus CoA + L-acylcarnitine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.21 ? x * 67000, SDS-PAGE Bos taurus