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Literature summary extracted from

  • Marshall, M.; Cohen, P.P.
    Ornithine transcarbamylase from Streptococcus faecalis and bovine liver. 3. Effects of chemical modifications of specific residues on ligand binding and enzymatic activity (1972), J. Biol. Chem., 247, 1669-1682.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.3.3 2,4,6-Trinitrobenzenesulfonate
-
 Bos taurus
2.1.3.3 2,4,6-Trinitrobenzenesulfonate 10 mM, almost complete inactivation Enterococcus faecalis
2.1.3.3 5,5'-dithiobis(2-nitrobenzoate)
-
 Bos taurus
2.1.3.3 5,5'-dithiobis(2-nitrobenzoate)
-
 Enterococcus faecalis
2.1.3.3 Acetylimidazole 50 mM, 95% inhibition at 25°C in 100 mM imidazole-HCl, pH 7.5 Enterococcus faecalis
2.1.3.3 cystamine complete inactivation, activity is completely recovered by incubation with 20 mM dithiothreitol Bos taurus
2.1.3.3 cystamine complete inactivation, activity is completely recovered by incubation with 20 mM dithiothreitol Enterococcus faecalis
2.1.3.3 dithiodiglycol 100 mM, inactivation at pH 9,0 Bos taurus
2.1.3.3 iodoacetate
-
 Bos taurus
2.1.3.3 iodoacetate
-
 Enterococcus faecalis
2.1.3.3 additional information effects of chemical modifications of specific residues on ligand binding and enzymatic activity Bos taurus
2.1.3.3 additional information effects of chemical modifications of specific residues on ligand binding and enzymatic activity Enterococcus faecalis
2.1.3.3 ornithine at high concentrations Enterococcus faecalis
2.1.3.3 p-hydroxymercuribenzoate inhibition is completely reversed by 2-mercaptoethanol Bos taurus
2.1.3.3 p-hydroxymercuribenzoate inhibition is completely reversed by 2-mercaptoethanol Enterococcus faecalis

Organism

EC Number Organism UniProt Comment Textmining
2.1.3.3 Bos taurus
-
-
-
2.1.3.3 Enterococcus faecalis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.3.3 carbamoyl phosphate + L-ornithine
-
 Bos taurus phosphate + L-citrulline
-
 ?
2.1.3.3 carbamoyl phosphate + L-ornithine
-
 Enterococcus faecalis phosphate + L-citrulline
-
 ?