Literature summary extracted from

Cox, R.
Polyamines inhibit DNA methylation in vitro (1979), Biochem. Biophys. Res. Commun., 86, 594-598.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.1.1.37	putrescine	1 mM, 42% inhibition	Rattus norvegicus
2.1.1.37	spermidine	1 mM, 59% inhibition	Rattus norvegicus
2.1.1.37	spermine	1 mM, 97% inhibition	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.37	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.37	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.37	S-adenosyl-L-methionine + DNA	-	Rattus norvegicus	S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine	-	?

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Release 2023.1 (January 2023)