Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Manen, C.A.; Russell, D.H.
    Comparative properties of rat liver and sea urchin eggs S-adenosyl-L-methionine decarboxylase (1974), Biochemistry, 13, 4729-4735.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.50 putrescine stimulation Rattus norvegicus
4.1.1.50 putrescine stimulation Lytechinus pictus
4.1.1.50 spermidine
-
 Rattus norvegicus
4.1.1.50 spermidine
-
 Lytechinus pictus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.50 4-Bromo-3-hydroxybenzoyloxyamine dihydrogen phosphate i.e. NSD-1055 Lytechinus pictus
4.1.1.50 Ca2+ 0.5 mM CaCl2 Rattus norvegicus
4.1.1.50 Cd2+ 0.5 mM CdCl2 Rattus norvegicus
4.1.1.50 Co2+ 0.5 mM CoCl2 Rattus norvegicus
4.1.1.50 EDTA above 1 mM Lytechinus pictus
4.1.1.50 FeCl2 0.5 mM Rattus norvegicus
4.1.1.50 iodoacetamide
-
 Lytechinus pictus
4.1.1.50 methylglyoxal bis(guanylhydrazone)
-
 Lytechinus pictus
4.1.1.50 methylglyoxal bis(guanylhydrazone)
-
 Rattus norvegicus
4.1.1.50 MgCl2 0.5 mM Rattus norvegicus
4.1.1.50 MnCl2 0.5 mM Rattus norvegicus
4.1.1.50 NEM
-
 Lytechinus pictus
4.1.1.50 NEM
-
 Rattus norvegicus
4.1.1.50 NH4Cl 0.5 mM Rattus norvegicus
4.1.1.50 Zn2+ 0.5 mM Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.50 56000
-
 gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.50 Lytechinus pictus
-
-
-
4.1.1.50 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.50
-
 Rattus norvegicus
4.1.1.50
-
 Lytechinus pictus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.50 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.50 additional information
-
-
 Rattus norvegicus
4.1.1.50 additional information
-
-
 Lytechinus pictus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.50 S-adenosyl-L-methionine
-
 Rattus norvegicus (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?
4.1.1.50 S-adenosyl-L-methionine
-
 Lytechinus pictus (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.50 7
-
 putrescine-stimulated enzyme Lytechinus pictus
4.1.1.50 7.5 8 spermidine-stimulated enzyme Lytechinus pictus