BRENDA - Enzyme Database

Aliphatic and aromatic inhibitors binding to the active site of catechol 2,3-dioxygenase from Pseudomonas putida mt-2

Bertini, I.; Briganti, F.; Scozzafava, A.; FEBS Lett. 343, 56-60 (1994)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.13.11.2
2-butanone
-
Pseudomonas putida
1.13.11.2
2-chlorophenol
-
Pseudomonas putida
1.13.11.2
2-Fluorophenol
-
Pseudomonas putida
1.13.11.2
2-hydroxyacetophenone
-
Pseudomonas putida
1.13.11.2
2-hydroxybenzyl alkohol
-
Pseudomonas putida
1.13.11.2
2-methoxyphenol
-
Pseudomonas putida
1.13.11.2
2-Pentanone
-
Pseudomonas putida
1.13.11.2
3-Pentanone
-
Pseudomonas putida
1.13.11.2
acetone
-
Pseudomonas putida
1.13.11.2
acetophenone
-
Pseudomonas putida
1.13.11.2
benzyl alkohol
-
Pseudomonas putida
1.13.11.2
ethanol
-
Pseudomonas putida
1.13.11.2
i-Propanol
-
Pseudomonas putida
1.13.11.2
methanol
-
Pseudomonas putida
1.13.11.2
n-butanol
-
Pseudomonas putida
1.13.11.2
n-Pentanol
-
Pseudomonas putida
1.13.11.2
n-Propanol
-
Pseudomonas putida
1.13.11.2
phenol
-
Pseudomonas putida
1.13.11.2
t-butanol
-
Pseudomonas putida
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
1.13.11.2
Fe2+
-
Pseudomonas putida
Organism
EC Number
Organism
UniProt
Commentary
Textmining
1.13.11.2
Pseudomonas putida
-
mt-2 paW1, ATCC 23973
-
Reaction
EC Number
Reaction
Commentary
Organism
Reaction ID
1.13.11.2
catechol + O2 = 2-hydroxymuconate-6-semialdehyde
mechanism
Pseudomonas putida
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
1.13.11.2
catechol + O2
-
439587
Pseudomonas putida
2-hydroxymuconate semialdehyde
-
439587
Pseudomonas putida
?
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
1.13.11.2
0.15
-
2-Pentanone
-
Pseudomonas putida
1.13.11.2
0.21
-
acetophenone
-
Pseudomonas putida
1.13.11.2
0.23
-
2-hydroxyacetophenone
-
Pseudomonas putida
1.13.11.2
0.23
-
2-methoxyphenol
-
Pseudomonas putida
1.13.11.2
0.35
-
2-butanone
-
Pseudomonas putida
1.13.11.2
0.52
-
2-chlorophenol
-
Pseudomonas putida
1.13.11.2
0.56
-
2-Fluorophenol
-
Pseudomonas putida
1.13.11.2
0.58
-
n-Pentanol
-
Pseudomonas putida
1.13.11.2
1.4
-
benzyl alkohol
-
Pseudomonas putida
1.13.11.2
1.7
-
n-butanol
-
Pseudomonas putida
1.13.11.2
3
-
3-Pentanone
-
Pseudomonas putida
1.13.11.2
5.3
-
2-hydroxybenzyl alkohol
-
Pseudomonas putida
1.13.11.2
7.1
-
phenol
-
Pseudomonas putida
1.13.11.2
21
-
n-Propanol
-
Pseudomonas putida
1.13.11.2
22
-
acetone
-
Pseudomonas putida
1.13.11.2
90
-
i-Propanol
-
Pseudomonas putida
1.13.11.2
147
-
ethanol
-
Pseudomonas putida
1.13.11.2
480
-
methanol
-
Pseudomonas putida
1.13.11.2
720
-
t-butanol
-
Pseudomonas putida
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.13.11.2
2-butanone
-
Pseudomonas putida
1.13.11.2
2-chlorophenol
-
Pseudomonas putida
1.13.11.2
2-Fluorophenol
-
Pseudomonas putida
1.13.11.2
2-hydroxyacetophenone
-
Pseudomonas putida
1.13.11.2
2-hydroxybenzyl alkohol
-
Pseudomonas putida
1.13.11.2
2-methoxyphenol
-
Pseudomonas putida
1.13.11.2
2-Pentanone
-
Pseudomonas putida
1.13.11.2
3-Pentanone
-
Pseudomonas putida
1.13.11.2
acetone
-
Pseudomonas putida
1.13.11.2
acetophenone
-
Pseudomonas putida
1.13.11.2
benzyl alkohol
-
Pseudomonas putida
1.13.11.2
ethanol
-
Pseudomonas putida
1.13.11.2
i-Propanol
-
Pseudomonas putida
1.13.11.2
methanol
-
Pseudomonas putida
1.13.11.2
n-butanol
-
Pseudomonas putida
1.13.11.2
n-Pentanol
-
Pseudomonas putida
1.13.11.2
n-Propanol
-
Pseudomonas putida
1.13.11.2
phenol
-
Pseudomonas putida
1.13.11.2
t-butanol
-
Pseudomonas putida
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
1.13.11.2
0.15
-
2-Pentanone
-
Pseudomonas putida
1.13.11.2
0.21
-
acetophenone
-
Pseudomonas putida
1.13.11.2
0.23
-
2-hydroxyacetophenone
-
Pseudomonas putida
1.13.11.2
0.23
-
2-methoxyphenol
-
Pseudomonas putida
1.13.11.2
0.35
-
2-butanone
-
Pseudomonas putida
1.13.11.2
0.52
-
2-chlorophenol
-
Pseudomonas putida
1.13.11.2
0.56
-
2-Fluorophenol
-
Pseudomonas putida
1.13.11.2
0.58
-
n-Pentanol
-
Pseudomonas putida
1.13.11.2
1.4
-
benzyl alkohol
-
Pseudomonas putida
1.13.11.2
1.7
-
n-butanol
-
Pseudomonas putida
1.13.11.2
3
-
3-Pentanone
-
Pseudomonas putida
1.13.11.2
5.3
-
2-hydroxybenzyl alkohol
-
Pseudomonas putida
1.13.11.2
7.1
-
phenol
-
Pseudomonas putida
1.13.11.2
21
-
n-Propanol
-
Pseudomonas putida
1.13.11.2
22
-
acetone
-
Pseudomonas putida
1.13.11.2
90
-
i-Propanol
-
Pseudomonas putida
1.13.11.2
147
-
ethanol
-
Pseudomonas putida
1.13.11.2
480
-
methanol
-
Pseudomonas putida
1.13.11.2
720
-
t-butanol
-
Pseudomonas putida
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
1.13.11.2
Fe2+
-
Pseudomonas putida
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
1.13.11.2
catechol + O2
-
439587
Pseudomonas putida
2-hydroxymuconate semialdehyde
-
439587
Pseudomonas putida
?