EC Number | General Stability | Organism |
---|---|---|
1.14.16.2 | 0.1 M 2-mercaptoethanol is necessary for stabilization during purification | Bos taurus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.14.16.2 | 2,2'-dipyridyl | - |
Bos taurus | |
1.14.16.2 | 2-methyl-L-tyrosine | - |
Bos taurus | |
1.14.16.2 | 3,4-dihydroxybenzoic acid | - |
Bos taurus | |
1.14.16.2 | alpha-Propyldihydroxyphenylacetamide | - |
Bos taurus | |
1.14.16.2 | dopamine | - |
Bos taurus | |
1.14.16.2 | L-Dopa | - |
Bos taurus | |
1.14.16.2 | norepinephrine | - |
Bos taurus | |
1.14.16.2 | phenylalanine | L-isomer, not D-isomer | Bos taurus | |
1.14.16.2 | phenylalanine | - |
Cavia porcellus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.16.2 | cytosol | - |
Bos taurus | 5829 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.16.2 | Iron | Fe2+ activates | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.16.2 | L-tyrosine + tetrahydrobiopterin + O2 | Cavia porcellus | - |
3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | - |
? | |
1.14.16.2 | L-tyrosine + tetrahydrobiopterin + O2 | Bos taurus | first step in biosynthesis of catecholamines such as norepinephrine, epinephrine and dopamine | 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.16.2 | Bos taurus | - |
- |
- |
1.14.16.2 | Cavia porcellus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.16.2 | - |
Bos taurus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.16.2 | adrenal medulla | - |
Bos taurus | - |
1.14.16.2 | brain | - |
Bos taurus | - |
1.14.16.2 | nervous system | sympathetic, innervated | Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.16.2 | L-tyrosine + 2-amino-4-hydroxy-6,7-dimethyltetrahydropterin + O2 | - |
Bos taurus | ? | - |
? | |
1.14.16.2 | L-tyrosine + tetrahydrobiopterin + O2 | - |
Cavia porcellus | 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | - |
? | |
1.14.16.2 | L-tyrosine + tetrahydrobiopterin + O2 | - |
Cavia porcellus | 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | 3,4-dihydroxy-L-phenylalanine is identical with dopa | ? | |
1.14.16.2 | L-tyrosine + tetrahydrobiopterin + O2 | - |
Bos taurus | 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | 3,4-dihydroxy-L-phenylalanine is identical with dopa | ? | |
1.14.16.2 | L-tyrosine + tetrahydrobiopterin + O2 | first step in biosynthesis of catecholamines such as norepinephrine, epinephrine and dopamine | Bos taurus | 3,4-dihydroxy-L-phenylalanine + dihydrobiopterin + H2O | - |
? | |
1.14.16.2 | L-tyrosine + tetrahydrofolic acid + O2 | - |
Bos taurus | ? | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.14.16.2 | 6.2 | - |
- |
Bos taurus |