BRENDA - Enzyme Database

Isolation and identification of 5-hydroxy-4-ketovaleric acid as a product of alpha-ketoglutarate:glyoxylate carboligase

Schlossberg, M.A.; Richert, D.A.; Bloom, R.J.; Westerfeld, W.W.; Biochemistry 7, 333-337 (1968)

Data extracted from this reference:

Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.2.1.5
Bos taurus
-
bovine
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.2.1.5
heart
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.2.1.5
2-oxoglutarate + glyoxylate
-
395929
Bos taurus
2-hydroxy-3-oxohexandioate + CO2
i. e. 2-hydroxy-3-oxoadipic acid
395929
Bos taurus
-
2.2.1.5
2-oxoglutarate + glyoxylate
-
395929
Bos taurus
2-hydroxy-3-oxohexandioate + CO2
further decarboxylation leads to 5-hydroxy-4-ketovaleric acid
395929
Bos taurus
-
Temperature Optimum [C]
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.2.1.5
37
-
enzyme assay at
Bos taurus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.2.1.5
7.1
-
enzyme assay at
Bos taurus
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
2.2.1.5
thiamine diphosphate
-
Bos taurus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
2.2.1.5
thiamine diphosphate
-
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.2.1.5
heart
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.2.1.5
2-oxoglutarate + glyoxylate
-
395929
Bos taurus
2-hydroxy-3-oxohexandioate + CO2
i. e. 2-hydroxy-3-oxoadipic acid
395929
Bos taurus
-
2.2.1.5
2-oxoglutarate + glyoxylate
-
395929
Bos taurus
2-hydroxy-3-oxohexandioate + CO2
further decarboxylation leads to 5-hydroxy-4-ketovaleric acid
395929
Bos taurus
-
Temperature Optimum [C] (protein specific)
EC Number
Temperature Optimum [C]
Temperature Optimum Maximum [C]
Commentary
Organism
2.2.1.5
37
-
enzyme assay at
Bos taurus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.2.1.5
7.1
-
enzyme assay at
Bos taurus