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Literature summary extracted from

  • Iio, M.; Kawaguchi, H.; Sakota, Y.; Otonari, J.; Nitahara, H.
    Effects of polyphenols, including flavonoids, on glutathione S-transferase and glutathione reductase (1993), Biosci. Biotechnol. Biochem., 57, 1678-1680.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.7 apigenin flavonone, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 Baicalin slightly, flavone glycoside, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 catechin slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 chrysin slightly, flavonone, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 epicatechin slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 epicatechin gallate slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 epigallocatechin slightly, catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 epigallocatechin gallate catechin, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 fisetin flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 gallic acid slightly Bos taurus
1.8.1.7 kaempferol slightly, flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 morin slightly, flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 myricetin flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 quercetin flavonol, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus
1.8.1.7 rutin slightly, flavonol glycoside, non-competitive with both NADPH and GSSG, influence on glutathione recognition Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.7 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.8.1.7 intestine mucosa Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.7 GSSG + NADPH
-
 Bos taurus glutathione + NADP+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.1.7 GR
-
 Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.7 NADPH
-
 Bos taurus