BRENDA - Enzyme Database

Monoamine oxidase contains a redox-active disulfide

Sablin, S.O.; Ramsay, R.R.; J. Biol. Chem. 273, 14074-14076 (1998)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.4.3.4
amphetamine
-
Homo sapiens
1.4.3.4
D-amphetamine
-
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.4.3.4
RCH2NH2 + H2O + O2
Homo sapiens
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
RCHO + NH3 + H2O2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.4.3.4
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.4.3.4
liver
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.4.3.4
RCH2NH2 + H2O + O2
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
394588
Homo sapiens
RCHO + NH3 + H2O2
-
-
-
?
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.4.3.4
flavin
speculation that, when an amine oxidized, electrons pass from the amine to the disulfide and then to the flavin
Homo sapiens
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.4.3.4
flavin
speculation that, when an amine oxidized, electrons pass from the amine to the disulfide and then to the flavin
Homo sapiens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.4.3.4
amphetamine
-
Homo sapiens
1.4.3.4
D-amphetamine
-
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.4.3.4
RCH2NH2 + H2O + O2
Homo sapiens
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
RCHO + NH3 + H2O2
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.4.3.4
liver
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.4.3.4
RCH2NH2 + H2O + O2
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
394588
Homo sapiens
RCHO + NH3 + H2O2
-
-
-
?