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Literature summary extracted from

  • Bernheim, M.L.C.; Hochstein, P.
    Reduction of hydroxylamine by rat liver mitochondria (1968), Arch. Biochem. Biophys., 124, 436-442.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.1.10 HgCl2 1 mM, complete inhibition Rattus norvegicus
1.7.1.10 KCN
-
 Rattus norvegicus
1.7.1.10 N-ethylmaleimide 1 mM, 50% inhibition Rattus norvegicus
1.7.1.10 p-chloromercuribenzoate 1 mM, complete inhibition Rattus norvegicus
1.7.1.10 p-hydroxymercuribenzoate
-
 Rattus norvegicus
1.7.1.10 phosphate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.7.1.10 mitochondrion
-
 Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.7.1.10 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.7.1.10 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.1.10 hydroxylamine + NADH enzyme also reduces anthranilic hydroxamic acid and nicotinic hydroxamic acid, affinity is about twenty times lower than for hydroxylamine Rattus norvegicus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH NADH is 1.5fold more effective than NADPH Rattus norvegicus NH3 + NAD+ + H2O
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.7.1.10 27
-
 stable for more than 1 h Rattus norvegicus
1.7.1.10 38
-
 1 h, inactivation Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.7.1.10 5.4 8.4 pH 5.4: considerable activity in Tris-maleate buffer, pH 8.4: about 50% activity Rattus norvegicus
1.7.1.10 5.5 7.2 pH 5.5: about 70% of activity maximum, pH 7.2: 50% activity Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.7.1.10 NADH
-
 Rattus norvegicus
1.7.1.10 NADPH about 65% of the activity with NADH Rattus norvegicus