Literature summary extracted from

Diatchuk, V.; Lotan, O.; Koshkin, V.; Wikstroem, P.; Pick, E.
Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds (1997), J. Biol. Chem., 272, 13292-13301.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
1.6.5.10	lithiumdodecylsulfate	-	Homo sapiens

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.6.5.10	expression of p47-phox and p67-phox in Sf9 cells	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.6.5.10	4-(2-aminoethyl)benzenesulfonylfluoride	-	Cavia porcellus
1.6.5.10	4-(2-aminoethyl)benzenesulfonylfluoride	0.206 mM, 50% inhibition, noncompetitive vs. NADPH, competitive vs. p47-phox in the concentration range of 0.5-2.0 mM	Homo sapiens
1.6.5.10	4-(amidino)benzenesulfonylfluoride	1.49 mM, 50% inhibition	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.6.5.10	Cavia porcellus	-	-	-
1.6.5.10	Homo sapiens	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.6.5.10	cytochrome b558 from neutrophils	Homo sapiens

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Release 2023.1 (January 2023)