EC Number | Cloned (Comment) | Organism |
---|---|---|
1.8.4.12 | gene selR, DNA and amino acid sequence determination and analysis, expression as His-tagged enzyme in Escherichia coli strain BL21(DE3) | Drosophila melanogaster |
1.8.4.12 | overexpression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3) | Mus musculus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.8.4.12 | selenium | selenoprotein | Mus musculus | |
1.8.4.12 | selenium | selenoprotein | Drosophila melanogaster | |
1.8.4.12 | Zn2+ | metalloenzyme, content determination | Mus musculus | |
1.8.4.12 | Zn2+ | metalloenzyme, content determination | Drosophila melanogaster |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin | Mus musculus | MsrB is absolute specific for the R-form, no activity with the S-form, pathway overview | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin | Drosophila melanogaster | MsrB is absolute specific for the R-form, no activity with the S-form, pathway overview | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.12 | additional information | Mus musculus | enzyme provides protection for the cell against oxidative stress | ? | - |
? | |
1.8.4.12 | additional information | Drosophila melanogaster | enzyme provides protection for the cell against oxidative stress | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.4.12 | Drosophila melanogaster | Q8INK9 | - |
- |
1.8.4.12 | Mus musculus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.4.12 | recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3) | Drosophila melanogaster |
1.8.4.12 | recombinant wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by heparin affinity chromatography | Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin | MsrB is absolute specific for the R-form, no activity with the S-form, pathway overview | Mus musculus | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin | MsrB is absolute specific for the R-form, no activity with the S-form, pathway overview | Drosophila melanogaster | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin | MsrB is absolute specific for the R-form, no activity with the S-form | Mus musculus | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.12 | L-methionine (R)-sulfoxide + thioredoxin | MsrB is absolute specific for the R-form, no activity with the S-form | Drosophila melanogaster | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.12 | additional information | enzyme provides protection for the cell against oxidative stress | Mus musculus | ? | - |
? | |
1.8.4.12 | additional information | enzyme provides protection for the cell against oxidative stress | Drosophila melanogaster | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.4.12 | methionine-R-sulfoxide reductase | - |
Mus musculus |
1.8.4.12 | methionine-R-sulfoxide reductase | - |
Drosophila melanogaster |
1.8.4.12 | selenoprotein R | - |
Mus musculus |
1.8.4.12 | selenoprotein R | - |
Drosophila melanogaster |
1.8.4.12 | SelR | - |
Mus musculus |
1.8.4.12 | SelR | - |
Drosophila melanogaster |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.4.12 | thioredoxin | - |
Mus musculus | |
1.8.4.12 | thioredoxin | - |
Drosophila melanogaster |