Literature summary extracted from

Harvey, R.J.; Dev, I.K.
Regulation in the folate pathway of Escherichia coli (1975), Adv. Enzyme Regul., 13, 99-124.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.5.1.5	ATP	-	Escherichia coli
1.5.1.5	GTP	-	Escherichia coli
1.5.1.5	N10-formyltetrahydrofolate	-	Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.5.1.5	5,10-methylenetetrahydrofolate + NADP+	Escherichia coli	-	5,10-methenyltetrahydrofolate + NADPH + H+	-	?
1.5.1.5	5,10-methylenetetrahydrofolate + NADP+	Escherichia coli B / ATCC 11303	-	5,10-methenyltetrahydrofolate + NADPH + H+	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.5.1.5	Escherichia coli	-	-	-
1.5.1.5	Escherichia coli B / ATCC 11303	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.5.1.5	5,10-methylenetetrahydrofolate + NADP+	-	Escherichia coli	5,10-methenyltetrahydrofolate + NADPH + H+	-	?
1.5.1.5	5,10-methylenetetrahydrofolate + NADP+	-	Escherichia coli B / ATCC 11303	5,10-methenyltetrahydrofolate + NADPH + H+	-	?

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Release 2023.1 (January 2023)