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Literature summary extracted from

  • Dann, J.G.; Harding, N.G.L.; Newbold, P.C.H.; Whiteley, J.M.
    Single-step purification of dihydrofolate reductases on pteridine matrices (1972), Biochem. J., 127, 28P-29P.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.3 folate NADPH stabilizes against intracellular inactivation via folate Lacticaseibacillus casei
1.5.1.3 methotrexate
-
 Lacticaseibacillus casei

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.3 Lacticaseibacillus casei
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.5.1.3 single-step purification on pteridine matrices Lacticaseibacillus casei

Renatured (Commentary)

EC Number Renatured (Comment) Organism
1.5.1.3 sodium docecyl sulfate causes irreversible inactivation Lacticaseibacillus casei

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.3 7,8-dihydrofolate + NADPH
-
 Lacticaseibacillus casei 5,6,7,8-tetrahydrofolate + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.3 NADPH
-
 Lacticaseibacillus casei