Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chu, R.; Varanasi, U.; Chu, S.; Lin, Y.; Usuda, N.; Rao, M.S.; Reddy, J.K.
    Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells (1995), J. Biol. Chem., 270, 4908-4915.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.3.6 expression as His-tagged protein in Spodoptera frugiperda cells via infection with Baculovirus Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.3.6 Detergents inactiviation via dissociation of subunits Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.3.6 0.01
-
 palmitoyl-CoA recombinant enzyme from Spodoptera frugiperda cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.3.6 peroxisome
-
 Homo sapiens 5777
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.3.6 21000
-
 ? * 51000 + ? * 21000, recombinant enzyme, SDS-PAGE Homo sapiens
1.3.3.6 51000
-
 ? * 51000 + ? * 21000, recombinant enzyme, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.6 acyl-CoA + O2 Homo sapiens involved in beta-oxidation of fatty acids in peroxisomes and glyoxysomes, respectively trans-2,3-dehydroacyl-CoA + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.6 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.3.6 recombinant His-tagged from Spodoptera frugiperda cells Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.6 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.6 acyl-CoA + O2 preference for C12-C18 acyl-CoA substrates Homo sapiens trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
1.3.3.6 acyl-CoA + O2 involved in beta-oxidation of fatty acids in peroxisomes and glyoxysomes, respectively Homo sapiens trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
1.3.3.6 palmitoyl-CoA + O2
-
 Homo sapiens 2-trans-hexadecenoyl-CoA + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.3.3.6 ? ? * 51000 + ? * 21000, recombinant enzyme, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
1.3.3.6 ACOX
-
 Homo sapiens
1.3.3.6 palmitoyl-CoA oxidase
-
 Homo sapiens