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Literature summary extracted from
- myo-Inositol-1-phosphate synthase. Characteristics of the enzyme and identification of its structural gene in yeast (1981), J. Biol. Chem., 256, 7077-7085.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | NH4+ | 21.5fold stimulation | Saccharomyces cerevisiae |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | 2-deoxy-D-glucose 6-phosphate | - |
Saccharomyces cerevisiae | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.5.1.4 | 1.18 | - |
D-glucose 6-phosphate | - |
Saccharomyces cerevisiae | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | K+ | slight stimulation | Saccharomyces cerevisiae | |
| 5.5.1.4 | Na+ | slight stimulation | Saccharomyces cerevisiae | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.4 | 62000 | - |
x * 62000, SDS-PAGE | Saccharomyces cerevisiae |
| 5.5.1.4 | 240000 | - |
gel filtration | Saccharomyces cerevisiae |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.5.1.4 | Saccharomyces cerevisiae | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.5.1.4 | - |
Saccharomyces cerevisiae |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.4 | additional information | - |
- |
Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.5.1.4 | D-Glucose 6-phosphate | - |
Saccharomyces cerevisiae | L-myo-Inositol 1-phosphate | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 5.5.1.4 | ? | x * 62000, SDS-PAGE | Saccharomyces cerevisiae |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.4 | 7 | - |
- |
Saccharomyces cerevisiae |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.4 | NAD+ | cofactor, Km: 0.008 mM | Saccharomyces cerevisiae | |
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Release 2023.1 (January 2023)
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